77772-62-4Relevant articles and documents
Synthesis of Azocanes from Piperidines via an Azetidinium Intermediate
Leverenz, Malte,Masson, Guillaume,Pardo, Domingo Gomez,Cossy, Janine
supporting information, p. 16325 - 16328 (2021/10/25)
α-Trifluoromethyl azocanes are accessible from 2-(trifluoropropan-2-ol) piperidines by metal-free ring-expansion involving a bicyclic azetidinium intermediate. The opening of the azetidinium intermediate was achieved by various nucleophiles (amines, alcoholates, carboxylates, phosphonates, halides and pseudo-halides) with an excellent regio- diastereo- and enantioselectivity and in good yields. The relative configuration of the piperidines and azocanes were assigned and the deprotected azocanes offer opportunities for further derivatization.
Phosphodiester alkylation with a quinone methide
Zhou, Qibing,Turnbull, Kenneth D.
, p. 2847 - 2851 (2007/10/03)
Despite the wide array of studies involving DNA alkylation and cleavage with quinone methide generating compounds, there have been no reports on the alkylation of phosphodiesters with quinone methides. We have investigated the reaction of dialkyl phosphat
Chemical synthesis of GDP-fucose analogs and their utilization by the Lewis α(1→4) fucosyltransferase
Gokhale,Hindsgaul,Palcic
, p. 1063 - 1071 (2007/10/02)
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