777854-97-4

Basic information

• Product Name: 2-iodoisophthalaldehyde
• Synonyms: 2-iodoisophthalaldehyde
• CAS NO: 777854-97-4
• Molecular Weight: 260.031
• Mol File: 777854-97-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-iodoisophthalaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodoisophthalaldehyde(777854-97-4)
• EPA Substance Registry System: 2-iodoisophthalaldehyde(777854-97-4)

Safety Data

• Hazardous Substances Data: 777854-97-4(Hazardous Substances Data)

Upstream product

• 81725-16-8 2-iodo-1,3-benzenedicarbonitrile 
• 626-17-5 benzene-1,3-dicarbonitrile 

Downstream Products

• 1268872-84-9 2,6-di[(4R,5R)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl]-1-hexylbenzene 
• 1268872-66-7 2,6-di-[(4R,5R)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl]iodobenzene 
• 1268872-79-2 2,6-di[(4R,5R)-4,5-di-tert-butyl-4,5-dihydro-1H-imidazol-2-yl]iodobenzene 
• 1268872-80-5 2,6-di[(4R,5R)-4,5-dimesityl-4,5-dihydro-1H-imidazol-2-yl]iodobenzene 
• 1268872-83-8 2,6-di[(4R,5R)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl]-1-phenylbenzene 
• 1268872-71-4 2-hexylbenzene-1,3-dicarbaldehyde 
• 1268872-94-1 2-(hex-1-ynyl)benzene-1,3-dicarbaldehyde 
• 1268872-77-0 C₂₈H₄₉IN₄ 

Relevant articles and documents

Pseudocyclic bis-N-heterocycle-stabilized iodanes - synthesis, characterization and applications

Bis-N-heterocycle-stabilized λ3-iodanes (BNHIs) based on azoles are introduced as novel structural motifs in hypervalent iodine chemistry. A performance test in a variety of benchmark reactions including sulfoxidations and phenol dearomatizations revealed a bis-N-bound pyrazole substituted BNHI as the most reactive derivative. Its solid-state structure was characterizedviaX-ray analysis implying strong intramolecular interactions between the pyrazole nitrogen atoms and the hypervalent iodine centre.

The reaction of aromatic dialdehydes with enantiopure 1,2-diamines: An expeditious route to enantiopure tricyclic amidines

The condensation of enantiopure 1,2-diamines with terephthalaldehyde, isophthalaldehyde or 2-iodo-, 2-alkyl- or 2-aryl-1,3-benzenedialdehydes in toluene followed by treatment with NBS in dichloromethane gives direct access to enantiopure 1,4-, and 1,3-di(4,5-dihydro-1H-imidazol-2-yl)benzenes (diamidines). The condensation of o-phthalaldehyde, and other ortho-disubstituted aromatic dialdehydes, with enantiopure 1,2-diamines, without NBS, gives enantiopure 3,5-dihydro-2H-imidazol-[2,1]-isoindoles.