77828-26-3Relevant articles and documents
Synthesis and cytotoxicity properties of amiodarone analogues
Bigler, Laurent,Spirli, Carlo,Fiorotto, Romina,Pettenazzo, Andrea,Duner, Elena,Baritussio, Aldo,Follath, Ferenc,Ha, Huy Riem
, p. 861 - 867 (2007)
Amiodarone (AMI) is a potent antiarrhythmic agent; however, its clinical use is limited due to numerous side effects. In order to investigate the structure-cytotoxicity relationship, AMI analogues were synthesized, and then, using rabbit alveolar macropha