77879-82-4

Basic information

• Product Name: 2-allyl-4-methyl-6-methoxyphenol
• Synonyms: 2-allyl-4-methyl-6-methoxyphenol
• CAS NO: 77879-82-4
• Molecular Weight: 178.231
• Mol File: 77879-82-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-allyl-4-methyl-6-methoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-allyl-4-methyl-6-methoxyphenol(77879-82-4)
• EPA Substance Registry System: 2-allyl-4-methyl-6-methoxyphenol(77879-82-4)

Safety Data

• Hazardous Substances Data: 77879-82-4(Hazardous Substances Data)

Usage

Source

Naturally occurring compound found in plants like clove oil, nutmeg, and cinnamon

Use in industries

Food and fragrance industries as a flavoring agent and aromatic compound

Scent

Sweet, spicy, clove-like

Properties

Antimicrobial and antioxidant

Applications

Traditional medicine and natural remedies for potential health benefits

Safety

May cause skin irritation and allergic reactions, precautions should be taken when handling or using products containing eugenol

Upstream product

• 201359-55-9 1-(allyloxy)-2-methoxy-4-methylbenzene 
• 93-51-6 2-Methoxy-4-methylphenol 
• 121-33-5 vanillin 

Downstream Products

• 857543-04-5 (2-hydroxy-3-methoxy-5-methyl-phenyl)-acetaldehyde 
• 369362-32-3 1-allyl-2,3-dimethoxy-5-methyl-benzene 
• 369362-33-4 (2,3-dimethoxy-5-methyl-phenyl)-acetaldehyde 
• 369362-34-5 2-(2,3-dimethoxy-5-methyl-phenyl)-propionic acid methyl ester 
• 96202-91-4 (2,3-dimethoxy-5-methyl-phenyl)-acetic acid methyl ester 
• 369362-36-7 2-(2,3-dimethoxy-5-methyl-phenyl)-2-methyl-pent-4-enal 
• 369362-38-9 4-(2,3-dimethoxy-5-methyl-phenyl)-4-methyl-cyclopent-2-enone 
• 369362-37-8 2-(2,3-dimethoxy-5-methyl-phenyl)-2-methyl-4-oxo-pentanal 
• 369362-35-6 2-(2,3-dimethoxy-5-methyl-phenyl)-2-methyl-pent-4-enoic acid methyl ester 
• 1256811-75-2 2-allyl-6-methoxy-4-methylphenyl trifluoromethanesulfonate 
• 5653-56-5 2,3-dimethoxy-5-methylbenzoic acid 
• 783333-03-9 (E)-5-(2-tert-butyldimethylsilyloxy-3-methoxy-5-methylphenyl)pent-2-enyl methyl carbonate 
• 783333-00-6 (E)-ethyl 5-(2-tert-butyldimethylsilyloxy-3-methoxy-5-methylphenyl)pent-2-enoate 
• 783333-04-0 (E)-5-(2-tert-butyldimethylsilyloxy-3-methoxy-5-methylphenyl)pent-2-en-1-ol 

Relevant articles and documents

Formal total synthesis of (±)-herbertenediol and (±)-mastigophorenes A and B

A simple and straightforward formal total synthesis of the sesquiterpene herbertenediol and its dimers mastigophorenes A and B, starting from vanillin, is described.

Synthesis of the landomycinone skeleton

The synthesis of the highly functionalized tetracyclic skeleton of landomycinone (2), the aglycon of landomycins, was performed using two pivotal steps relying on metal-catalyzed reactions. They are (1) a [2 + 2 + 2] cycloaddition of alkynes promoted by W

Synthesis of chiral chromans by the Pd-catalyzed asymmetric allylic alkylation (AAA): Scope, mechanism, and applications

The Pd-catalyzed asymmetric allylic alkylation (AAA) of phenol allyl carbonates serves as an efficient strategy to construct the allylic C-O bond allowing access to chiral chromans in up to 98% ee. The effect of pH and the influence of olefin geometry, as well as substitution pattern on the ee and the absolute configuration of the chiral chromans were explored in detail. These observations suggest a mechanism involving the cyclization of the more reactive π-allyl palladium diastereomeric intermediate as the enantiodiscriminating step (Curtin-Hammett conditions). This methodology led to the enantioselective synthesis of the vitamin E core, the first enantioselective total synthesis of (+)-clusifoliol and (-)-siccanin, and the synthesis of an advanced intermediate toward (+)-rhododaurichromanic acid A.