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78184-67-5

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  • 1-Azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(1-hydroxyethyl)-3,7-dioxo-, (4-nitrophenyl)methyl ester, [2S-[2a,5b,6b(S*)]]- (9CI)

    Cas No: 78184-67-5

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78184-67-5 Usage

Description

(4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate is a complex chemical compound characterized by a nitrophenyl group, a carboxylate ester group, a bicyclic ring system, a hydroxyethyl group, and a ketone functional group. Its stereochemistry is specified as (2S,5R,6S), which indicates the configuration of the chiral centers in the molecule. This unique structure and the presence of various functional groups may endow the compound with potential pharmaceutical or biological applications.

Uses

Used in Pharmaceutical Industry:
(4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate is used as a pharmaceutical candidate for the development of new drugs due to its unique structure and functional groups. (4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate's potential applications may include the treatment of various diseases and conditions, given its ability to interact with biological targets and modulate biological pathways.
Used in Research and Development:
In the field of research and development, (4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate serves as a valuable compound for studying the effects of stereochemistry on biological activity. Its unique structure allows researchers to investigate the role of chiral centers in drug design and development, potentially leading to the discovery of more effective and selective therapeutic agents.
Used in Chemical Synthesis:
(4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate can be utilized as a key intermediate in the synthesis of other complex organic compounds. Its versatile structure and functional groups make it a suitable building block for the preparation of various pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Analytical Chemistry:
(4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate's unique structure and functional groups also make it a potential candidate for use in analytical chemistry. (4-nitrophenyl)methyl [2S-[2alpha,5beta,6beta(S)]]-6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate can be employed as a chiral selector in chromatographic techniques, enabling the separation and analysis of enantiomers and other chiral compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 78184-67-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,1,8 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78184-67:
(7*7)+(6*8)+(5*1)+(4*8)+(3*4)+(2*6)+(1*7)=165
165 % 10 = 5
So 78184-67-5 is a valid CAS Registry Number.

78184-67-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-nitrobenzyl (2S,5R,6S)-6-[(R)-1-hydroxyethyl]-3,7-dioxo-1-azabicyclo-[3.2.0]heptane-2-carboxylate

1.2 Other means of identification

Product number -
Other names (2S,5R,6S)-4-nitrobenzyl 6-((R)-1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:78184-67-5 SDS

78184-67-5Relevant articles and documents

METHOD OF PREPARING INTERMEDIATES OF PENEM ANTIBIOTICS

-

Page/Page column 28; 30, (2009/06/27)

The present invention relates to a method of preparing bicyclic keto esters, which are intermediates for carbapenem-based antibiotics. The method of preparing carbapenem-based antibiotic intermediates according to the present invention has not only the fast reaction rate using co-catalysts and specific reaction solvents which may be allowed to have high activity of rhodium catalysts, but also reduces the amount of expensive rhodium catalysts. Therefore, the present invention is very economical and useful, in industrial aspects.

A PRACTICAL SYNTHESIS OF (+/-)-THIENAMYCIN

Melillo, D.G.,Shinkai, I.,Liu, T.,Ryan, K.,Sletzinger, M.

, p. 2783 - 2786 (2007/10/02)

An efficient and operationally simply synthesis of (+/-)-thienamycin is described.

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