78208-11-4

Basic information

• Product Name: levomethadone nitrile hydrochloride
• Synonyms: levomethadone nitrile hydrochloride
• CAS NO: 78208-11-4
• Molecular Weight: 314.858
• Mol File: 78208-11-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: levomethadone nitrile hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: levomethadone nitrile hydrochloride(78208-11-4)
• EPA Substance Registry System: levomethadone nitrile hydrochloride(78208-11-4)

Safety Data

• Hazardous Substances Data: 78208-11-4(Hazardous Substances Data)

Upstream product

• 86-29-3 Diphenylacetonitrile 

Downstream Products

• 5967-73-7 (R)-methadone hydrochloride 

Relevant articles and documents

SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE

A method for synthesizing levomethadone hydrochloride including producing (R)-2-(dimethylamino)propan-1-ol by reducing N,N-dimethyl-D-alanine using borax, forming (R)-1-chloro-N,N-dimethylpropane-2-amine hydrochloride by chlorinating the (R)-2-(dimethylamino)propan-1-ol, synthesizing levomethadone nitrile hydrochloride by mixing the (R)-1-chloro-N,N-dimethylpropane-2-amine and diphenylacetonitrile with potassium t-butoxide and producing levomethadone hydrochloride by exposing the levomethadone nitrile hydrochloride to a Grignard reagent.