78296-37-4

Basic information

• Product Name: 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID;4-hydroxy-6-phenylpicolinic acid
• CAS NO: 78296-37-4
• Molecular Formula: C₁₂H₉NO₃
• Molecular Weight: 215.2
• Mol File: 78296-37-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 614.7°C at 760 mmHg
• Flash Point: 325.5°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 5.76E-16mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID(78296-37-4)
• EPA Substance Registry System: 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID(78296-37-4)

Safety Data

• Hazardous Substances Data: 78296-37-4(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-6-phenylpyridine-2-carboxylic acid is a chemical compound with a molecular formula C12H9NO3. It is a derivative of pyridine and contains a hydroxyl group, a phenyl group, and a carboxylic acid group. 4-HYDROXY-6-PHENYLPYRIDINE-2-CARBOXYLIC ACID is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs. Its structure and properties make it suitable for use in the development of drugs targeting specific biological pathways and disease processes. It is an important intermediate in the production of active pharmaceutical ingredients and is used in the synthesis of various drugs such as anti-cancer agents, antimicrobial agents, and anti-inflammatory drugs.

InChI:InChI=1/C12H9NO3/c14-9-6-10(8-4-2-1-3-5-8)13-11(7-9)12(15)16/h1-7H,(H,13,14)(H,15,16)

Upstream product

• 1154-90-1 Ethyl 5,6-dibromo-2,4-dioxo-6-phenylhexanoate 
• 1027-41-4 ethyl (E)-2,4-dioxo-6-phenylhex-5-enoate 
• 1083-01-8 4-oxo-6-phenyl-4H-pyrane-2-carboxylic acid 
• 7500-03-0 2-Methyl-6-phenyl-1,4-dihydropyridin-4-on 
• 26567-78-2 (Z)-4-(phenylamino)-3-penten-2-one 
• 123-54-6 acetylacetone 
• 412923-41-2 4-chloro-2-methyl-6-phenyl-pyridine 
• 85814-93-3 4-hydroxy-6-phenylpyridine-2-carboxamide 
• 2397-77-5 Ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate 

Downstream Products

• 1191263-83-8 4-chloro-6-phenyl-pyridine-1-carboxylic acid ethyl ester 
• 1214284-46-4 methyl 4-hydroxy-6-phenylpyridine-2-carboxylate 
• 1188276-66-5 ethyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate 
• 1214284-55-5 pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate 
• 1214284-54-4 butyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate 
• 1214284-56-6 hexyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate 
• 1019929-28-2 4-((S)-3-methoxy-pyrrolidin-1-yl)-6-phenyl-pyridine-2-carboxylic acid 
• 1191264-25-1 4-(2-methoxy-ethoxy)-6-phenyl-pyridine-2-carboxylic acid 
• 1191264-30-8 6-phenyl-4-(tetrahydro-furan-3-yloxy)-pyridine-2-carboxylic acid 
• 1191263-86-1 4-((R)-4-(diethoxy-phosphoryl)-2-([4-((S)-3-methoxy-pyrrolidin-1-yl)-6-phenyl-pyridine-2-carbonyl]-amino)-butyryl)-piperazine-1-carboxylic acid ethyl ester 
• 1191263-36-1 4-((R)-2-([4-((S)-3-methoxy-pyrrolidin-1-yl)-6-phenyl-pyridine-2-carbonyl]-amino)-4-phosphono-butyryl)-piperazine-1-carboxylic acid ethyl ester 
• 1152096-35-9 ethyl 4-hydroxy-6-phenylpyridine-2-carboxylate 
• 1241726-43-1 4-hydroxy-6-phenylpyridine-2-carbohydrazide 
• 1191264-31-9 4-[(R)-3-(diethoxy-phosphoryl)-2-({6-phenyl-4-[(tetrahydro-furan-3-yl)oxy]-pyridine-2-carbonyl}-amino)-propionyl]-piperazine-1-carboxylic acid butyl ester 

Relevant articles and documents

SUBSTITUTED 2-PHENYL-PYRIDINE DERIVATIVES

The present invention relates to compounds of formula I wherein R1, R2, R4, R5, Ra, Rb, n, W and Z are as defined in the application, their preparation and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.

New derivatives of 6-phenylcomanic acid

Ethyl 6-phenylcomanic acid with hydrazine hydrate and hydroxylamine gives 4-oxo-6-phenyl-4H/-pyran-2-carbohydrazide and 4-oxo-6-phenyl-4H-pyran-2- carbohydroxamic acid, whereas 6-phenylcomanic acid with ammonia in aqueous DMSO gives 4-hydroxy-6-phenylpico

Studies on antiallergic agents. I. Phenyl-substituted heterocycles with a 5-tetrazolyl or N-(5-tetrazolyl)carbamoyl group

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