783-04-0 Usage
Description
1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE, with the molecular formula C10H8F3NO2, is a nitroalkene derivative featuring a trifluoromethyl group attached to a phenyl ring and a nitro group on the second carbon of a propene chain. 1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE is known for its high reactivity due to the presence of the trifluoromethyl group, making it a valuable asset in organic synthesis. However, it is crucial to handle this compound with caution, as it can pose risks to health and the environment.
Uses
Used in Pharmaceutical Synthesis:
1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE is utilized as an intermediate in the production of various pharmaceuticals. Its unique structure and reactivity allow for the creation of a wide range of medicinal compounds, contributing to the development of new treatments and therapies.
Used in Agrochemical Production:
1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE also serves as an intermediate in the synthesis of agrochemicals, which are essential for the agricultural industry to protect crops from pests and diseases, ensuring food security and crop yield.
Used as a Reagent in Organic Reactions:
1-(3-(TRIFLUOROMETHYL)PHENYL)-2-NITROPROPENE is employed as a reagent to introduce the trifluoromethyl group into other molecules during organic reactions. The trifluoromethyl group is known to enhance the properties of molecules, such as their stability, lipophilicity, and metabolic stability, making this compound a valuable tool in the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 783-04-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,8 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 783-04:
(5*7)+(4*8)+(3*3)+(2*0)+(1*4)=80
80 % 10 = 0
So 783-04-0 is a valid CAS Registry Number.
783-04-0Relevant articles and documents
Synthesis of 14C norfenfluramine
Ronco,Renault,Rapin,Compagnon
, p. 549 - 556,550,555,556 (2007/10/13)
The starting materials 14C-Trifluoromethylbenzoic acid and 14C bistrifluoromethyl-3 -benzophenone were prepared by carbonation of appropriate Grignard reagents. The labelled benzophenone was oxidized in high yield to give 14C-trifluoromethylbenzoic acid. This 14C carboxylic compound was transformed into aldehyde which was condensed with nitroethane to form 14C-trifluoromethyl-3-phenyl-1-nitro-2-propene, 1-9. The latter compound was reduced with lithium aluminium hydride to give 14C-norfenfluramine. The overall yield was 45,5% at a specific activity of 1,65 mCi/mM.
