783368-48-9 Usage
Description
(R)-3-aMino-1-benzylazepan-2-one, with the molecular formula C15H20N2O, is a chiral azepane derivative characterized by its seven-membered ring with a nitrogen atom and a benzyl group attached to the nitrogen atom. (R)-3-aMino-1-benzylazepan-2-one's (R) configuration denotes a specific three-dimensional orientation, which may contribute to its potential applications in medicinal chemistry and other research fields due to the presence of an amino group and a carbonyl group.
Uses
Used in Medicinal Chemistry:
(R)-3-aMino-1-benzylazepan-2-one is used as a building block for the synthesis of various organic compounds, particularly in medicinal chemistry. Its unique structure, including the aromatic benzyl group and the functional groups, allows for the development of new pharmaceuticals with potential therapeutic applications.
Used in Research and Development:
In the field of research and development, (R)-3-aMino-1-benzylazepan-2-one serves as a valuable compound for exploring its properties and potential interactions with biological systems. Its chiral nature and structural features make it an interesting candidate for studying molecular recognition and the development of targeted therapies.
Please note that the specific applications and industries for (R)-3-aMino-1-benzylazepan-2-one may not be widely recognized or established, as the compound name provided may not be a known compound. The information presented here is based on the given chemical name and its potential implications in the fields of medicinal chemistry and research.
Check Digit Verification of cas no
The CAS Registry Mumber 783368-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,3,3,6 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 783368-48:
(8*7)+(7*8)+(6*3)+(5*3)+(4*6)+(3*8)+(2*4)+(1*8)=209
209 % 10 = 9
So 783368-48-9 is a valid CAS Registry Number.
783368-48-9Relevant articles and documents
Synthesis of bengamide E analogues and their cytotoxic activity
Phi, Thi Dao,Mai, Huong Doan Thi,Tran, Van Hieu,Vu, Van Loi,Truong, Bich Ngan,Tran, Tuan Anh,Chau, Van Minh,Pham, Van Cuong
, p. 1830 - 1833 (2017/04/21)
A series of bengamide E analogues were prepared from the corresponding polyketide chain and amino acids via amide coupling reactions. Opening of the polyketide chain lactone ring with α-aminolactams was successfully achieved under microwave irradiation in the presence of sodium 2-ethyl hexanoate. A cytotoxic activity evaluation against a panel of cancer cell lines (KB, HepG-2, Lu-1, MCF-7, HL-60 and Hela) indicated that the 2′R analogues were generally more cytotoxic than the 2′S analogues. Additionally, several analogues exhibited selective inhibition against various cancer cell lines: compounds 32a and 32b selectively inhibited MCF-7 cells, while 33b and 35b were more sensitive toward Lu-1 and HepG-2, respectively. Notably, some of the synthetic analogues possess cytotoxic activities with IC50 values less than 1?μM.
