78635-91-3Relevant articles and documents
BIS-(N,N-DIALKYLAMINO)ALKOXYPHOSPHINES AS A NEW CLASS OF PHOSPHITE COUPLING AGENT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES
Lee, Hyun-Jae,Moon, Sung-Hwan
, p. 1229 - 1232 (1984)
A new class of bifunctional phosphitylating agent which is stable but readily activatable for the efficient synthesis of oligonucleotides is described.
Hindered Dialkylamino Nucleoside Phosphite Reagents in the Synthesis of Two DNA 51-Mers
Adams, Steven P.,Kavka, Kamila S.,Wykes, Evan J.,Holder, Sarah B.,Galluppi, Gerald R.
, p. 661 - 663 (2007/10/02)
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DEOXYNUCLEOSIDE PHOSPHORAMIDITES-A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS
Beaucage, S. L.,Caruthers, M. H.
, p. 1859 - 1862 (2007/10/02)
The development of a new class of nucleoside phosphites is described.These compounds are stable to normal laboratory conditions, are activated by mild acid treatment, and are observed to react essentially quantitatively with protected nucleosides.