78787-80-1

Basic information

• Product Name: 2,6-dimethyl-9H-carbazole
• Synonyms: 2,6-Dimethyl-9H-carbazole; 9H-Carbazole, 2,6-dimethyl-; Carbazole, 2,6-dimethyl-
• CAS NO: 78787-80-1
• Molecular Formula: C₁₄H₁₃N
• Molecular Weight: 195.2597
• Mol File: 78787-80-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 383°C at 760 mmHg
• Flash Point: 170.8°C
• Density: 1.158g/cm³
• Vapor Pressure: 9.99E-06mmHg at 25°C
• Refractive Index: 1.712
• CAS DataBase Reference: 2,6-dimethyl-9H-carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-9H-carbazole(78787-80-1)
• EPA Substance Registry System: 2,6-dimethyl-9H-carbazole(78787-80-1)

Safety Data

• Hazardous Substances Data: 78787-80-1(Hazardous Substances Data)

Upstream product

• 249611-60-7 2,6-dimethyl-2,3,4,9-tetrahydro-1H-carbazole 
• 785-86-4 1,3-di(p-tolyl)triaz-1-ene 
• 14192-62-2 2,6-dimethyl-2,3,4,9-tetrahydro-carbazol-1-one 
• 1451422-90-4 C₂₁H₂₃N₃O₂S 
• 591-24-2 3-Methylcyclohexanone 
• 539-44-6 N-4-methylphenylhydrazine 
• 106-49-0 p-toluidine 
• 116668-35-0 4’,5-dimethyl[1,1’-biphenyl]-2-amine 
• 855468-23-4 5-methyl-1-p-tolyl-1H-1,2,3-benzotriazole 

Relevant articles and documents

A tandem reduction-oxidation protocol for the conversion of 1-keto-1,2,3,4-tetrahydrocarbazoles to carbazoles via tosylhydrazones through microwave assistance: Efficient synthesis of glycozoline, clausenalene, glycozolicine, and deoxycarbazomycin B and the total synthesis of murrayafoline A

A novel and efficient methodology for the synthesis of carbazoles from 1-keto-1,2,3,4-tetrahydrocarbazoles via the corresponding tosylsulfonhydrazones by a one-pot tandem reduction-oxidation protocol using a combination of NaBH4 and Pd-C on MgSO4·7H2O, a solid support, under microwave is developed. The reaction is successfully extended toward the synthesis of several naturally occurring carbazole alkaloids, namely 3-methylcarbazole, glycozoline, clausenalene, glycozolicine, murrayafoline A, and deoxycarbazomycin B, a carbazole derivative that is known to have a promising antimicrobial activity.