788-09-0

Basic information

• Product Name: N-(1,3-diphenylpropan-2-yl)formamide
• CAS NO: 788-09-0
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.3123
• Mol File: 788-09-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 445.6°C at 760 mmHg
• Flash Point: 269.5°C
• Density: 1.075g/cm³
• Vapor Pressure: 3.91E-08mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: N-(1,3-diphenylpropan-2-yl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-diphenylpropan-2-yl)formamide(788-09-0)
• EPA Substance Registry System: N-(1,3-diphenylpropan-2-yl)formamide(788-09-0)

Safety Data

• Hazardous Substances Data: 788-09-0(Hazardous Substances Data)

Upstream product

• 77287-34-4 formamide 
• 102-04-5 1,3-Diphenylpropanone 
• 201230-82-2 carbon monoxide 
• 1788-31-4 1,3-diphenylpropan-2-one oxime 
• 540-69-2 ammonium formate 

Downstream Products

• 77414-37-0 phenyl-acetic acid-(1-benzyl-2-phenyl-ethylamide) 
• 97356-32-6 1,3-dibenzyl-3,4-dihydro-isoquinoline 
• 4275-43-8 1-benzyl-2-phenylethylamine 

Relevant articles and documents

Probes of the Active Site of Norepinephrine N-Methyltransferase: Effect of Hydrophobic and Hydrophilic Interactions on Side-Chain Binding of Amphetamine and α-Methylbenzylamine

A series of ω-substituted analogues of amphetamine and α-methylbenzylamine were prepared and evaluated as inhibitors of norepinephrine N-methyltransferase (NMT).These included several alkyl side chain extended analogues (1-5), as well as the terminally hydroxylated derivatives phenylalanol (6a) and Phenylglycinol (7a).None of the alkyl-substituted derivatives displayed appreciable activity as inhibitors; however, the hydroxylated analogues were up to twofold more potent than the parent compounds.The positive contribution of the side-chain hydroxy suggests that theterminal methyl group of the lead compounds is situated close to a hydrophilic area or hydrogen bonding functional group within the active site.