78831-87-5

Basic information

• Product Name: 2,4-DIMETHYLBENZYL BROMIDE
• Synonyms: 2,4-DIMETHYLBENZYL BROMIDE;Benzene, 1-(bromomethyl)-2,4-dimethyl- (7CI, 9CI);2,4-Dimethylbenzyl bromide,98%;Benzene, 1-(bromomethyl)-2,4-dimethyl-;2,4-DiMethylbenzyl broMide, 98% 1GR;1-(Bromomethyl)-2,4-dimethyl-benzene;1-Bromomethyl-2,4-dimethylbenzene
• CAS NO: 78831-87-5
• Molecular Formula: C₉H₁₁Br
• Molecular Weight: 199.09
• Product Categories: HALOMETYL
• Mol File: 78831-87-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 15℃
• Boiling Point: 235℃
• Flash Point: 102℃
• Appearance: Clear colorless to light yellow/Liquid
• Density: 1.314
• Vapor Pressure: 0.0769mmHg at 25°C
• Refractive Index: 1.568-1.57
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,4-DIMETHYLBENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHYLBENZYL BROMIDE(78831-87-5)
• EPA Substance Registry System: 2,4-DIMETHYLBENZYL BROMIDE(78831-87-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• RIDADR: 3265
• Hazardous Substances Data: 78831-87-5(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to light yellow liquid

InChI:InChI=1/C9H11Br/c1-7-3-4-9(6-10)8(2)5-7/h3-5H,6H2,1-2H3

Upstream product

• 824-55-5 2,4-dimethyl-benzyl chloride 
• 50-00-0 formaldehyd 
• 108-38-3 m-xylene 
• 16308-92-2 2,4-dimethylbenzyl alcohol 

Downstream Products

• 883865-46-1 2-(2,4-dimethyl-benzylamino)-4-oxo-4,5-dihydro-imidazole-1-carboxylic acid benzyl ester 
• 68429-53-8 (2,4-dimethylphenyl)acetonitrile 
• 1338224-99-9 C₁₈H₁₇N₃S 
• 1338225-31-2 C₁₈H₁₇N₃O 
• 1413061-29-6 2,4-dimethylbenzaldehyde O-(phenylmethyl)oxime 
• 1383539-69-2 4-cyclohexyl-2-(2,4-dimethyl-benzylsulfanyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile 
• 41402-96-4 2,4-Dimethyl-1-p-tolylsulfanylmethyl-benzene 
• 41402-95-3 (2,4-dimethylbenzyl)(phenyl)sulfane 

Relevant articles and documents

Synthesis of 2,2-dimethyl-3-(3-methyl phenyl)propanal and its derivatives

An alternative approach to the synthesis of 2,2-dimethyl-3-(3-methylphenyl) propanal and its derivatives was described. 2,2-Dimethyl-3-(3-methylphenyl) propanal and its derivatives were obtained in middle yields from various substituted alkylaromtics, via bromination and alkylation. Its feature of fragrance was green, reminiscent of leaves, with flowery-aldehydic aspects. Copyright

Paracyclophanes. Part 58 [1]. On the use of the stilbene-phenanthrene photocyclization in [2.2]paracyclophane chemistry

The application of the stilbene→phenanthrene photocyclization to [2.2]paracyclophane chemistry has been investigated. For the model system 4-styryl[2.2]paracyclophane (2) to [2.2]phenanthrenoparacyclophane (3) the reaction allows the introduction of alkyl substituants in the 6-, 7-, 8- and 9-position of the phenanthrene moiety. However, when the substituent in the 9-position (bay area of phenanthrene nucleus) becomes too large, viz. tert-butyl, no ring closure is observed anymore. The side products of the process (ring cleavage products of the cyclophane core such as 9 and 10) have been characterized for the first time. Extension of the condensed deck is possible leading to PAH-phanes as demonstrated by the preparation of the chrysenophanes 45 and 60; the cyclization to novel helicenophanes such as 50 also takes place without difficulties. In the case of 1,2-di(4-[2.2] paracyclophanyl)ethene (63) the triply-layered hydrocarbon 65 is produced on irradiation in small amounts.

Synthesis and antirhinovirus activity of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines

A series of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)purines was synthesized and tested for antirhinovirus activity. Most of the compounds were synthesized by alkylation of 6-chloro-2-(trifluoromethyl)-9H-purine with the appropriate benzyl halide followed by displacement of the chloro group with dimethylamine. Alternatively, 6-(dimethylamino)-2-(trifluoromethyl)purine was alkylated with the appropriate benzyl halide. Although several different aryl substituents provided compounds with IC50's = 0.03 μM against rhinovirus serotype 1B, no congener was significantly more active than the parent 2. Twenty-three compounds were tested against 18 other serotypes, but none exhibited a uniform profile of activity.