79251-44-8

Basic information

• Product Name: Cyclohexanol, 2-phenoxy-, (1R,2R)-rel-
• CAS NO: 79251-44-8
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 79251-44-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 2-phenoxy-, (1R,2R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 2-phenoxy-, (1R,2R)-rel-(79251-44-8)
• EPA Substance Registry System: Cyclohexanol, 2-phenoxy-, (1R,2R)-rel-(79251-44-8)

Safety Data

• Hazardous Substances Data: 79251-44-8(Hazardous Substances Data)

Upstream product

• 110-83-8 cyclohexene 
• 108-95-2 phenol 
• 822-87-7 2-Chlorocyclohexanone 
• 286-20-4 cyclohexene oxide 
• 1460-57-7 trans-1,2-cyclohexandiol 
• 28899-97-0 triphenylbismuth(V) diacetate 
• 121906-87-4 (+/-)-trans-1-acetoxy-2-phenoxycyclohexane 
• 286-20-4 cyclohexane-1,2-epoxide 
• 109571-58-6 cyano-(2-phenoxy-cyclohexyliden)-acetic acid ethyl ester 
• 14004-19-4 2-phenoxycyclohexanone 

Downstream Products

• 905294-11-3 (2,2-dimethoxy-cyclohexyloxy)-benzene 
• 102998-34-5 Dimethyl-[2-((1S,2S)-2-phenoxy-cyclohexyloxy)-ethyl]-amine; compound with oxalic acid 
• 14004-19-4 2-phenoxycyclohexanone 
• 125992-56-5 (-)-(1R,2R)-2-phenoxycyclohexyl acetate 
• 125992-55-4 (+)-trans-2-phenoxycyclohexanol-1-ol 
• 102998-30-1 1-[2-((1S,2S)-2-Phenoxy-cyclohexyloxy)-ethyl]-piperidine; compound with oxalic acid 
• 102998-38-9 1-[3-((1S,2S)-2-Phenoxy-cyclohexyloxy)-propyl]-piperidine; compound with oxalic acid 
• 109395-92-8 (+/-)-trans-1-phenoxy-2-(toluene-4-sulfonyloxy)-cyclohexane 
• 121906-87-4 (+/-)-trans-1-acetoxy-2-phenoxycyclohexane 
• 102998-32-3 Diethyl-[2-((1S,2S)-2-phenoxy-cyclohexyloxy)-ethyl]-amine; compound with oxalic acid 

Relevant articles and documents

An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions

An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)2[BiCl6] Cl·H2O (1 mol %). This catalyst can be reused several times without significant loss of activity.

CONVENIENT ENANTIOSELECTIVE HYDROLYSIS OF RACEMIC trans-1-ACETOXY-2-ARYLOXYCYCLOHEXANES BY CRUDE PIG LIVER ACETONE POWDER (PLAP)

Crude pig liver acetone powder (PLAP) hydrolyzes trans-1-acetoxy-2-aryloxycyclohexanes enantioselectively to produce the corresponding alcohols in high optical purities.

Conversion of One Hydroxy Group in a Diol to a Phenyl Ether with Triphenylbismuth Diacetate, a New Glycol Reaction Showing Strong Axial Preference in Six-Membered Rings

After being refluxed for a few hours, a dichloromethane solution of a diol with triphenylbismuth diacetate gave in most cases excellent yields of a monophenyl ether.No diphenylated products were found.Tertiary hydroxy groups were only phenylated in bis tertiary diols, and then in poor yield.Increasing the distance between the hydroxy groups up to six carbon atoms decreased the speed of the reaction which nevertheless was still preparatively useful.Diols in flexible rings behaved like their acyclic counterparts.The course of the reaction was also examined with someconformationally rigid molecules: trans-4-tert-butyl-cis-2-hydroxycyclohexanol, trans-4-tert-butyl-trans-2-hydroxycyclohexanol, cholestane-2α,3α-diol, cholestane-2α,3β-diol, and pyranoside derivatives with the α-D-gluco, α-D-manno, α-D-galacto, and α-D-allo configurations.The phenylations of cis-diols were strongly regioselective for axial epimers, while those of trans, bis equatorial diols were undiscriminate and often much slower.A feasible general mechanism is proposed to explain these results.