822-87-7Relevant articles and documents
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Allinger et al.
, p. 5876,5881 (1960)
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Synthesis of Ti-Al binary oxides and their catalytic application for C-H halogenation of phenols, aldehydes and ketones
Su, Peigen,Fan, Chao,Yu, Heng,Wang, Wanqin,Jia, Xin,Rao, Qifan,Fu, Chenxi,Zhang, Donghua,Huang, Benhua,Pan, Cheng,Zheng, Aqun,Sun, Yang
, (2019/06/13)
Traditional C–H halogenation of organic compounds often requires corrosive agent or harsh condition, and current researches are focused on the use of noble metals as catalyst. In order to give an efficient, benign, activity-adjustable and cost-effective system for halogenation, a series of Ti-Al mixed oxides are prepared as catalyst through sol-gel in this work. Characterizations reveal all catalysts contain more aluminum than titanium, but preparative conditions affect their composition and crystallinity. Monitoring of particle size, zeta potential and UV–vis of preparative solution reveals that formation of catalyst colloids undergoes chemical reaction, affecting catalyst morphology. In halogenation, all catalysts show moderate to high activities, copper chloride proves to be an effective halogen source rather than sodium chloride. The chlorination and bromination are better than iodization, phenol and ketone appear to be more appropriate substrates than aldehyde. Additionally, oxide backbone of catalyst is more durable than its organic components during recycling. This study may provide new catalytic materials for progress of C–H activation.
Method for preparing o-chlorocyclohexanone by using cyclohexanone by-product lightweight oil
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Paragraph 0016; 0017; 0018; 0019; 0020, (2018/04/01)
The invention discloses a method for preparing o-chlorocyclohexanone through lightweight oil, wherein the lightweight oil is the by-product obtained from cyclohexanone preparation through oxidation ofcyclohexane, and the o-chlorocyclohexanone is prepared in the presence of an auxiliary agent and a catalyst by completely utilizing the cyclohexene oxide in the lightweight oil through ring opening,oxidation and other reactions. According to the present invention, with the method, the disadvantages of more impurities, harsh reaction condition or complex product purification and the like in the prior art are solved. The method comprises: in the presence of an auxiliary agent, carrying out a reaction on lightweight oil containing 1 mole of cyclohexene oxide and 1-2 moles of a hydrogen chloridesolution for 1-4 h at a temperature of 10-60 DEG C to generate 2-chlorocyclohexanol, distilling to remove the relatively low boiling point components to obtain high-purity 2-chlorocyclohexanol, carrying out a reaction on the high-purity 2-chlorocyclohexanol as a raw material and a certain amount of an oxidizing agent, washing, separating, rectifying, and collecting the distillate at a temperatureof 203-204 DEG C to obtain the o-chlorocyclohexanone with the purity of more than 99%, wherein the yield of the o-chlorocyclohexanone is more than 90%.
Rearrangement Reaction Based on the Structure of N-Fluoro- N-alkyl Benzenesulfonamide
Wang, Han-Ying,Pu, Xiao-Qiu,Yang, Xian-Jin
, p. 13103 - 13110 (2018/10/20)
A novel rearrangement reaction based on the structure of N-fluoro-N-alkyl benzenesulfonamide was developed. The reaction proceeded readily at 50 °C in formic acid and generated a variety of benzenesulfonamides and aldehydes or ketones simultaneously. The reaction mechanism is believed to be a concerted mechanism that consist of 1,2-aryl migration with the departure of fluorine anion via an SN2 mechanism. This rearrangement reaction features an interesting reaction mechanism, mild reaction conditions, simple operations, and a broad substrate scope.