79286-74-1

Basic information

• Product Name: 3-ACETAMIDOPYRROLIDINE
• Synonyms: N-(3-Pyrrolidinyl)acetamide;3-ACETAMIDOPYRROLIDINE;3-ACETAMIDOPYRROLIDINE 97+%;ACETAMINOPYRROLIDINE;Acetylaminopyrrolidine;3-(Acetylamino)pyrrolidine;3-(N-Acetamino) pyrrolidine;3-Acetaminopyrrolidine
• CAS NO: 79286-74-1
• Molecular Formula: C₆H₁₂N₂O
• Molecular Weight: 128.17
• Product Categories: 3-Aminopyrrolidines;3-Aminopyrrolidines (Racemic)
• Mol File: 79286-74-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 306.8°C at 760 mmHg
• Flash Point: 150.8°C
• Appearance: /
• Density: 1.09
• Vapor Pressure: 0.000752mmHg at 25°C
• Refractive Index: 1.5040-1.5090
• Storage Temp.: Refrigerator
• PKA: 15.94±0.20(Predicted)
• CAS DataBase Reference: 3-ACETAMIDOPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETAMIDOPYRROLIDINE(79286-74-1)
• EPA Substance Registry System: 3-ACETAMIDOPYRROLIDINE(79286-74-1)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 79286-74-1(Hazardous Substances Data)

Usage

Uses

N-3-Pyrrolidinyl Acetamide is a useful building block.

InChI:InChI=1/C6H12N2O/c1-5(9)8-6-2-3-7-4-6/h6-7H,2-4H2,1H3,(H,8,9)

Upstream product

• 18471-40-4 1-Benzyl-3-aminopyrrolidine 
• 28506-01-6 3-acetylamino-1-benzylpyrrolidine 

Downstream Products

• 114610-20-7 7-(3-Acetylamino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-4-oxo-1,4-dihydro-pyrido[2,3-c]pyridazine-3-carboxylic acid ethyl ester 
• 98106-42-4 7-(3-Acetylamino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 100491-94-9 ethyl 7-(3-acetylamino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 117239-37-9 ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-acetamidopyrrolidin-1-yl)-8-nitro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 100491-97-2 7-(3-Acetylamino-pyrrolidin-1-yl)-6-fluoro-1-(4-fluoro-phenyl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 105859-11-8 ethyl 1-(4-fluorophenyl)-6,8-difluoro-7-(3-acetamidopyrrolidin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 105859-12-9 ethyl 1-(2,4-difluorophenyl)-6,8-difluoro-7-(3-acetamidopyrrolidin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 105572-98-3 7-(3-acetylamino-pyrrolidin-1-yl)-6-fluoro-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 1107645-70-4 N-[1-(2-chloro-acetyl)-pyrrolidin-3-yl]-acetamide 

Relevant articles and documents

Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs

A series of analogs of DM235 and MN19, characterized by rings with different size, have been prepared and evaluated for their nootropic activity in the mouse passive-avoidance test. It was found that the optimal ring size for the analogs of DM235, showing endocyclic both amidic groups, is 6 or 7 atoms. For the compounds structurally related to MN19, carrying an exocyclic amide group, the piperidine ring is the moiety which gives the most interesting compounds.

Tetracyclic benzimidazole derivatives and combinatorial libraries thereof

The present invention relates to novel tetracyclic benzimidazole derivative compounds of the following formula: wherein R1to R10have the meanings described in here. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing tetracyclic benzimidazole derivative compounds.

Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments

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