79323-12-9

Basic information

• Product Name: 4-benzoylpyrrolo<1,2-a>quinoxaline
• Synonyms: 4-benzoylpyrrolo<1,2-a>quinoxaline
• CAS NO: 79323-12-9
• Molecular Weight: 272.306
• Mol File: 79323-12-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-benzoylpyrrolo<1,2-a>quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzoylpyrrolo<1,2-a>quinoxaline(79323-12-9)
• EPA Substance Registry System: 4-benzoylpyrrolo<1,2-a>quinoxaline(79323-12-9)

Safety Data

• Hazardous Substances Data: 79323-12-9(Hazardous Substances Data)

Upstream product

• 6025-60-1 2-(1H-pyrrol-1-yl)aniline 
• 90560-40-0 phenyllactic acid 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 98-88-4 benzoyl chloride 
• 536-74-3 phenylacetylene 
• 234-95-7 pyrrolo[1,2-a]quinoxaline 
• 209974-60-7 1-[(2-formylamino)phenyl]pyrrole 
• 100-52-7 benzaldehyde 
• 350829-07-1 1-[2-isocyanophenyl]-1H-pyrrole 
• 79323-08-3 5-benzoyl-4-cyano-4,5-dihydropyrrolo<1,2-a>quinoxaline 

Relevant articles and documents

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocyclesviadecarboxylative oxidative annulation reaction

A metal-free and efficient procedure for the synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and indolo[1,2-a]quinoxaline has been developed. The key features of our method include thein situgeneration of aldehyde from α-hydroxy acid in the presence of TBHP (tert-butyl hydrogen peroxide), and further condensation with various amines, followed by intramolecular cyclization and subsequent oxidation to afford the corresponding quinoxalines, quinazolinones derivatives in moderate to high yields.

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y1 and Y2. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones.

Reissert Compound Studies. XLI. Synthesis and Reactions of the Pyrroloquinoxaline Reissert Compound and its Analogs.

Reaction of pyrroloquinoxaline, either by the phase-transfer catalyst method or by the trimethylsilyl cyanide method, yielded the Reissert compound, 5-benzoyl-4-cyano-4,5-dihydropyrroloquinoxaline.This Reissert compound rearranged to 4-benzo