79421-43-5

Basic information

• Product Name: 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE
• Synonyms: 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE;4-(4-hydroxy-1-piperidinyl)benzonitrile;Benzonitrile,4-(4-hydroxy-1-piperidinyl)-;4-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile(WX640378)
• CAS NO: 79421-43-5
• Molecular Formula: C₁₂H₁₄N₂O
• Molecular Weight: 202.25
• Mol File: 79421-43-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 102-103 °C(Solv: benzene (71-43-2); hexane (110-54-3))
• Boiling Point: 407.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• PKA: 14.73±0.20(Predicted)
• CAS DataBase Reference: 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE(79421-43-5)
• EPA Substance Registry System: 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE(79421-43-5)

Safety Data

• Hazardous Substances Data: 79421-43-5(Hazardous Substances Data)

Usage

General Description

4-(4-Hydroxy-piperidin-1-yl)-benzonitrile is a chemical compound with the molecular formula C13H14N2O. It is a benzonitrile derivative with a hydroxy-piperidine substituent. 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE is used in the synthesis of pharmaceuticals and organic compounds, and it can also act as a building block in the preparation of other chemical compounds. It has potential application in medicinal chemistry for the development of drugs targeting various biological pathways and diseases. Overall, 4-(4-Hydroxy-piperidin-1-yl)-benzonitrile is a versatile chemical that has a variety of potential uses in the fields of chemistry and medicine.

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 1194-02-1 4-fluorobenzonitrile 

Downstream Products

• 871013-57-9 C₁₂H₁₈N₂O 
• 281234-93-3 4-(4-hydroxypiperidin-1-yl)benzoic acid 
• 182201-45-2 C₂₀H₁₉N₃ 
• 182201-44-1 N-(4-cyanophenyl)-4-(4-cyanobenzylidinyl)piperidine 
• 79421-46-8 4-(4-oxo-piperidin-1-yl)-benzonitrile 
• 1334717-80-4 7-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1334717-79-1 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1334718-08-9 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethyl)phenoxy)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1334718-05-6 6-chloro-N-(4-(4-(4-chlorophenoxy)piperidin-1-yl)benzyl)-2-ethylimidazo[1,2-a]pyridine-3-carboxamide 
• 1334718-10-3 6-chloro-2-ethyl-N-(4-(4-(4-fluorophenoxy)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide 

Relevant articles and documents

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Synthesis and structure-activity studies of side chain analogues of the anti-tubercular agent, Q203

The anti-tubercular activity of 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl)imidazo [1,2-a]pyridine-3-carboxamide (Q203) is modified by varying its side chain. In this study, we synthesized Q203 analogues with different side

New oxadiazole derivatives

The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or N-oxide thereof: and its use in the treatment of diseases which are susceptible to improvement by sphingosine-1-phosphate (S1P1) receptor agonists.