871013-57-9 Usage
Description
1-(4-AMINOMETHYL-PHENYL)-PIPERIDIN-4-OL is a chemical compound belonging to the piperidine class of organic compounds. It is a derivative of piperidine with a phenyl and an amino substituent at positions 1 and 4, respectively. This piperidinol contains a piperidine ring with an alcohol functional group at the 4-position and is used in medicinal chemistry as a building block for the synthesis of various pharmaceutical drugs. Additionally, it can act as a ligand in the development of new therapeutic agents, making it a valuable chemical in the field of pharmaceutical research and development.
Uses
Used in Pharmaceutical Research and Development:
1-(4-AMINOMETHYL-PHENYL)-PIPERIDIN-4-OL is used as a building block for the synthesis of various pharmaceutical drugs due to its unique chemical structure and properties.
Used in Medicinal Chemistry:
1-(4-AMINOMETHYL-PHENYL)-PIPERIDIN-4-OL is used as a ligand in the development of new therapeutic agents, contributing to the advancement of novel treatments for various diseases and conditions.
Used in the Treatment of Various Diseases and Conditions:
1-(4-AMINOMETHYL-PHENYL)-PIPERIDIN-4-OL has potential applications in the treatment of various diseases and conditions, making it a valuable chemical in the field of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 871013-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,0,1 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 871013-57:
(8*8)+(7*7)+(6*1)+(5*0)+(4*1)+(3*3)+(2*5)+(1*7)=149
149 % 10 = 9
So 871013-57-9 is a valid CAS Registry Number.
871013-57-9Relevant articles and documents
Synthesis and evaluation of 4-substituted benzylamine derivatives as β-tryptase inhibitors
Miyazaki, Yutaka,Kato, Yutaka,Manabe, Tadashi,Shimada, Hiroyasu,Mizuno, Masashi,Egusa, Takayuki,Ohkouchi, Munetaka,Shiromizu, Ikuya,Matsusue, Tomokazu,Yamamoto, Ichiro
, p. 2986 - 2990 (2008/09/20)
Since β-tryptase is considered a critical mediator of asthma, potent tryptase inhibitors may be useful as new agents for the treatment of asthma. We investigated 4-substituted benzylamine derivatives and obtained M58539 (15h) as a potent inhibitor of β-tryptase (IC50 = 5.0 nM) with high selectivity against other serine proteases, low molecular weight, c log P value less than 5, lack of amidino and guanidino groups, and independence of Zn2+ ion.
