794535-38-9Relevant articles and documents
Potent and highly selective DP1 antagonists with 2,3,4,9-tetrahydro-1H- carbazole as pharmacophore
Li, Lianhai,Beaulieu, Christian,Carriere, Marie-Claude,Denis, Danielle,Greig, Gillian,Guay, Daniel,O'Neill, Gary,Zamboni, Robert,Wang, Zhaoyin
scheme or table, p. 7462 - 7465 (2011/02/21)
We discovered that the introduction of a methyl group to the benzylic position of the N-benzyl group in lead compound 1a has a dramatic effect on improving the binding selectivity of this ligand for the prostanoid receptors DP1 (receptor for prostaglandin
NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
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, (2008/06/13)
The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating dyslipidemias. Pharmaceutical compositions and methods of use are also included.
METHOD OF TREATING ATHEROSCLEROSIS, DYSLIPIDEMIAS AND RELATED CONDITIONS
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Page/Page column 54, (2008/06/13)
A method of treating atherosclerosis is disclosed wherein nicotinic acid or another nicotinic acid receptor agonist is administered to the patient in combination with a DP receptor antagonist. The DP receptor antagonist is administered to reduce, prevent