79679-49-5 Usage
General Description
2,3-Dihydrobenzofuran-5-ethanol tosylate is a chemical compound that is commonly used as an intermediate in organic synthesis. It is a tosylate ester of 2,3-dihydrobenzofuran-5-ethanol, and is often utilized in the production of pharmaceuticals and agrochemicals. 2,3-Dihydrobenzofuran-5-ethanol Tosylate also has potential applications in medicinal chemistry and drug discovery, as well as in the development of new materials and fine chemicals. It is important to handle and store 2,3-Dihydrobenzofuran-5-ethanol tosylate with care, as it is classified as a hazardous chemical and may pose health and environmental risks if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 79679-49-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,6,7 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 79679-49:
(7*7)+(6*9)+(5*6)+(4*7)+(3*9)+(2*4)+(1*9)=205
205 % 10 = 5
So 79679-49-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H18O4S/c1-13-2-5-16(6-3-13)22(18,19)21-11-8-14-4-7-17-15(12-14)9-10-20-17/h2-7,12H,8-11H2,1H3
79679-49-5Relevant articles and documents
AN IMPROVED PROCESS FOR THE PREPARATION OF DARIFENACIN HYDROBROMIDE
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Page/Page column 10-11, (2011/06/26)
The present invention relates to an improved process for the preparation of Darifenacin hydrobromide of Formula (I). (i) condensing 3-(S)-(-)-1l-carbamoyl-1,1-diphenylmethyl)pyrrolidine (III), or its salt, with a compound of Formula XIII in the presence of a. base in a solvent, wherein X represents Cl, Br, C1-3 alkyl sulfonate or C6-10 arγl sulfonate; to produce (S)-2-[1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3- pyrrolidinyl]-2,2-diphenylacetamide (Darifenacin) (Ia), (ix) treating (S)-2-[1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl]- 2,2-diphenylacetamide (Darifenacin) (Ia) with an acid in a solvent and water mixture, (x) isolating pure (S)-2-[1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3- pyrrolidinyl]-2,2-diphenylacetamide (Darifenacin) (Ia), (xi) treating pure Darifenacin (Ia) with HBr to produce Darifenacin hydrobromide (I).
