80269-52-9Relevant articles and documents
Cascade Formation of C3-Unsymmetric Spirooxindoles via PhI(OAc)2-Mediated Oxidative C?C/C?N Bond Formation
Sun, Jiyun,Li, Guangchen,Zhang, Guangtao,Cong, Ying,An, Xuechan,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 2476 - 2481 (2018)
A series of C3-unsymmetric spirooxindoles were achieved by reaction of diphenylmalonamides with PhI(OAc)2 (PIDA) under metal-free conditions. Control experiments suggest that the hypervalent iodine-mediated reaction undergoes a cascade process involving an oxidative C?C bond formation preceeding an oxidative C?N bond formation. (Figure presented.).
