80348-66-9

Basic information

• Product Name: 4-hydroxyisoxazole
• Synonyms: 4-hydroxyisoxazole
• CAS NO: 80348-66-9
• Molecular Formula: C₃H₃NO₂
• Molecular Weight: 85
• Mol File: 80348-66-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 221.5 °C at 760 mmHg
• Flash Point: 87.7 °C
• Appearance: /
• Density: 1.331 g/cm³
• CAS DataBase Reference: 4-hydroxyisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxyisoxazole(80348-66-9)
• EPA Substance Registry System: 4-hydroxyisoxazole(80348-66-9)

Safety Data

• Hazardous Substances Data: 80348-66-9(Hazardous Substances Data)

Usage

General Description

4-hydroxyisoxazole is a chemical compound with the molecular formula C3H3NO2. It is a heterocyclic compound containing both oxygen and nitrogen atoms in a five-membered ring structure. 4-hydroxyisoxazole is a derivative of isoxazole, and it is commonly used in organic synthesis as a building block for various pharmaceuticals, agrochemicals, and materials science applications. It has also shown potential as an anticonvulsant and analgesic agent in pharmacological studies. Additionally, 4-hydroxyisoxazole has been investigated for its potential neuroprotective and anti-inflammatory properties, making it a subject of interest in the development of new therapeutic agents.

Upstream product

• 928664-98-6 4-isoxazoleboronic acid pinacol ester 
• 80370-41-8 2-(isoxazol-4-yl)propan-2-ol 

Downstream Products

• 83259-38-5 4-methoxyisoxazole 

Relevant articles and documents

Generation of an 4-Isoxazolyl Anion Species: Facile Access to Multifunctionalized Isoxazoles

A direct functionalization of unsubstituted isoxazole (1) was achieved by generation of 4-isoxazolyl anion species (3). An efficient 4-iodination of isoxazole and halogen–metal exchange reaction using a turbo Grignard reagent (iPrMgCl? LiCl) were essentia

Pyrrolidine modulators of chemokine receptor activity

The present invention is directed to pyrrolidine compounds of the formula 1: (wherein R1, R2, R3, R4, R5, R6and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

ISOLATION, STRUCTURE AND SYNTHESIS OF 4-HYDROXYISOXAZOLE (TRIUMFEROL), A SEED GERMINATION INHIBITOR FROM AN AFRICAN PLANT

The isolation, characterization and an efficient synthesis of 4-hydroxyisoxazole 1, a plant growth regulator isolated from an African plant is reported.It is a new compound, which despite the simple structure, had eluded synthesis.