80364-46-1

Basic information

• Product Name: N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE
• Synonyms: ACETAMIDE, N-(6-CHLORO-2-PYRIDINYL)-;N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE;N-(6-Chloro-pyridin-2-yl)-acetaMide
• CAS NO: 80364-46-1
• Molecular Formula: C₇H₇ClN₂O
• Molecular Weight: 170.598
• Mol File: 80364-46-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE(80364-46-1)
• EPA Substance Registry System: N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE(80364-46-1)

Safety Data

• Hazardous Substances Data: 80364-46-1(Hazardous Substances Data)

Usage

General Description

N-(6-chloro-2-pyridinyl)acetamide is a chemical compound with the molecular formula C7H7ClN2O. It is a white to off-white solid that is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE is classified as an acetamide, containing a pyridinyl group and a chlorine atom. It is typically synthesized using standard organic chemistry techniques, and its properties and potential uses are of interest to researchers and scientists in various fields. Additionally, it is important to handle N-(6-chloro-2-pyridinyl)acetamide with care and follow proper safety protocols due to its potential hazards.

Upstream product

• 1075-62-3 N-(6-aminopyridin-2-yl)acetamide 
• 20885-12-5 2-chloro-6-fluoropyridine 
• 124-42-5 acetamidine hydrochloride 
• 45644-21-1 6-chloropyridin-2-amine 
• 75-36-5 acetyl chloride 
• 60-35-5 acetamide 
• 2402-78-0 2,6-dichloropyridine 

Downstream Products

• 827342-84-7 2-acetamido-6-chloropyridine N-oxide 
• 442129-37-5 6-amino-2-chloro-3-methylpyridine 
• 827342-86-9 2-(tert-butyloxycarbonylamino)-6-chloropyridine N-oxide 
• 45644-21-1 6-chloropyridin-2-amine 

Relevant articles and documents

Access to 2-pyridinylamide and imidazopyridine from 2-fluoropyridine and amidine hydrochloride

Under catalyst-free conditions, an efficient method to synthesize 2-pyridinylamides has been developed, and the protocol uses inexpensive and readily available 2-fluoropyridine and amidine derivatives as the starting materials. Simultaneously, the copper-catalysed approach to imidazopyridine derivatives has been established with high chemoselectivity and regiospecificity. The results suggest that the nitrogen-heterocycles containing iodide substituents can also be compatible for the reaction via the cascade Ullmann-type coupling, and the nucleophilic substitution reaction provides the target products in a one-pot manner.

4, 5-DIHYDRO-LH-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES

Mineralocorticoid receptor antagonists (MRa), pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetic nephropathy and hypertension in mammals, including humans.