80841-48-1

Basic information

• Product Name: 9-[2-Methoxy-4-(methylsulfonylamino)phenylamino]-N,5-dimethyl-4-acridinecarboxamide 2-hydroxyethanesulfonate
• Synonyms: Asulacrine isethionate; Amsalog; NSC-343499; CI-921; 2-hydroxyethanesulfonic acid - 9-({2-methoxy-4-[(methylsulfonyl)amino]phenyl}amino)-N,5-dimethylacridine-4-carboxamide (1:1)
• CAS NO: 80841-48-1
• Molecular Formula: C₂H₆O₄S*C₂₄H₂₄N₄O₄S
• Molecular Weight: 590.6684
• Mol File: 80841-48-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 861.2°C at 760 mmHg
• Flash Point: 474.6°C
• Vapor Pressure: 1.27E-31mmHg at 25°C
• CAS DataBase Reference: 9-[2-Methoxy-4-(methylsulfonylamino)phenylamino]-N,5-dimethyl-4-acridinecarboxamide 2-hydroxyethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 9-[2-Methoxy-4-(methylsulfonylamino)phenylamino]-N,5-dimethyl-4-acridinecarboxamide 2-hydroxyethanesulfonate(80841-48-1)
• EPA Substance Registry System: 9-[2-Methoxy-4-(methylsulfonylamino)phenylamino]-N,5-dimethyl-4-acridinecarboxamide 2-hydroxyethanesulfonate(80841-48-1)

Safety Data

• Hazardous Substances Data: 80841-48-1(Hazardous Substances Data)

Upstream product

• 92138-15-3 5-methyl-9-chloroacridine-4-carbonyl chloride 
• 57165-06-7 N-(4-amino-3-methoxyphenyl)methanesulfonamide 
• 88915-00-8 9-chloro-4-methyl-5-<(methylamino)carbonyl>acridine 
• 107-36-8 2-hydroxyethanesulfonic acid 
• 80841-47-0 [14C]-Asulacrine 

Relevant articles and documents

Anticancer anilinoacridines. A process synthesis of the disubstituted amsacrine analog CI-921

An improved process for the synthesis of bulk quantities of the clinical amsacrine analog CI-921 is reported. Described also are detailed analytical and spectroscopic data for this agent.