81028-70-8

Basic information

• Product Name: 3-phenoxythiophene-2,5-dicarboxylic acid
• CAS NO: 81028-70-8
• Molecular Weight: 264.259
• Mol File: 81028-70-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-phenoxythiophene-2,5-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenoxythiophene-2,5-dicarboxylic acid(81028-70-8)
• EPA Substance Registry System: 3-phenoxythiophene-2,5-dicarboxylic acid(81028-70-8)

Safety Data

• Hazardous Substances Data: 81028-70-8(Hazardous Substances Data)

Upstream product

• 63285-84-7 3-phenoxythiophene 
• 124-38-9 carbon dioxide 
• 108-95-2 phenol 

Relevant articles and documents

Application of Regioselective Thiophene Lithiation to the Synthesis of Thiophene Analogues of Xanthones and Thioxanthones

Treatment of 3-(p-tolyloxy)thiophene (3) with phenyllithium followed by carbonation with CO2 was found to be a convenient procedure for the preparation of the thiophene-2-carboxylic acid 4, which was cyclized to 5 with PPE.Treatment of 3 with butyllithium followed by carbonation gave the thiophene-2,5-dicarboxylic acid 8 which was cyclized to 9.Alkaline permanganate oxidation of 4 gave the diacid 10, which was cyclized to the tricyclic acid 11.Similar lithiation reactions were observed with additional 3-(aryloxy)thiophenes and with 3-(arylthio)thiophenes, and xanthone analogues were prepared from the resulting intermediates.