81053-26-1

Basic information

• Product Name: aridanin
• Synonyms: aridanin
• CAS NO: 81053-26-1
• Molecular Formula: C38H61NO8
• Molecular Weight: 659.89284
• Mol File: 81053-26-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 794.7°Cat760mmHg
• Flash Point: 434.4°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 3.35E-29mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: aridanin(CAS DataBase Reference)
• NIST Chemistry Reference: aridanin(81053-26-1)
• EPA Substance Registry System: aridanin(81053-26-1)

Safety Data

• Hazardous Substances Data: 81053-26-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C38H61NO8/c1-21(41)39-28-30(43)29(42)24(20-40)46-31(28)47-27-12-13-35(6)25(34(27,4)5)11-14-37(8)26(35)10-9-22-23-19-33(2,3)15-17-38(23,32(44)45)18-16-36(22,37)7/h9,23-31,40,42-43H,10-20H2,1-8H3,(H,39,41)(H,44,45)/t23-,24+,25-,26+,27-,28+,29+,30+,31-,35-,36+,37+,38-/m0/s1

Upstream product

• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 908835-49-4 28-O-benzyl 3-O-[3′,4′,6′-tri-O-acetyl-2′-deoxy-2′-phthalimido-β-D-glucopyranosyl] oleanolic ester 
• 146728-55-4 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-(α/β)-D-glucopyranosyl trichloroacetimidate 
• 172847-90-4 p-methylphenyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 303114-51-4 oleanolic acid benzyl ester 
• 81053-27-2 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside oleanolic acid 

Relevant articles and documents

Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamine

A series of N-acyl, N-alkoxycarbonyl, and N-alkylcarbamoyl derivatives of 2′-deoxy-glucosyl bearing oleanolic saponins were synthesized and evaluated against HL-60, PC-3, and HT29 tumor cancer cells. The SAR studies revealed that the activity increased in order of conjugation of 2′ -amino group with carbamate > amide > urea derivatives. Lengthening the alkyl chain increased the cytotoxicity, the peak activity was found to around heptyl to nonyl substitutions. 2′-N-heptoxycarbonyl derivative 56 was found to be the most cytotoxic (IC50 = 0.76 μM) against HL-60 cells. Due to the interesting SARs of alkyl substitutions, we hypothesized that their location in the cell was different, and pursued a location study using 2′-(4″-pentynoylamino) 2′-deoxy-glucosyl OA, which suggested that these compounds distributed mainly in the cytosol.

Entada Saponins (ES) II and IV from the Bark of Entada phaseoloides

The structures of entada saponins II and IV, isolated from the bark of Entada phaseoloides (L.) Merrill (Leguminosae), were elucidated as 3-O-2)-α-L-arabinopyranosyl-(1->6)>4)>-2-acetamido-2-deoxy-β-D-glucopyranosyl-28-O-3)-β-D-xylopyranosyl(1->2)>4)>-6-O-((6R)-6-hydroxy-2,6-dimethyl-(2E)-2,7-octadienoyl)-β-D-glucopyranosyl olenolic acid (1) and entagenic acid (3).Keywords - Entada phaseoloides; Leguminosae; triterpene saponin; 13C-NMR chemical shift; entada saponin II; entada saponin IV