81096-93-7

Basic information

• Product Name: (R)-4-Benzyloxy-1,3-butanediol
• Synonyms: (R)-4-Benzyloxy-1,3-butanediol;(R)-4-Benzyloxy-1,3-butanediol
• CAS NO: 81096-93-7
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24
• Product Categories: Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry
• Mol File: 81096-93-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 138 °C / 0.5mmHg
• Flash Point: 169.326°C
• Appearance: /
• Density: 1.131g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 10 ° (C=1, MeOH)
• Storage Temp.: Refrigerator
• PKA: 13.99±0.20(Predicted)
• CAS DataBase Reference: (R)-4-Benzyloxy-1,3-butanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Benzyloxy-1,3-butanediol(81096-93-7)
• EPA Substance Registry System: (R)-4-Benzyloxy-1,3-butanediol(81096-93-7)

Safety Data

• Hazardous Substances Data: 81096-93-7(Hazardous Substances Data)

Usage

General Description

(R)-4-Benzyloxy-1,3-butanediol is an organic compound with the molecular formula C13H18O3. It is a chiral compound, meaning it exists in two enantiomeric forms, with this chemical being the (R)-enantiomer. (R)-4-Benzyloxy-1,3-butanediol is commonly used as a chiral building block in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of flavors and fragrances. Additionally, (R)-4-Benzyloxy-1,3-butanediol has been explored for its potential antimicrobial and anticancer properties. Its unique chemical structure and versatile applications make it a valuable compound in the field of organic chemistry.

InChI:InChI=1/C11H16O3/c12-7-6-11(13)9-14-8-10-4-2-1-3-5-10/h1-5,11-13H,6-9H2/t11-/m1/s1

Upstream product

• 69152-87-0 4-benzyloxycrotonaldehyde 
• 78469-85-9 (2S,3S)-4-benzyloxy-2,3-epoxy-1-butanol 
• 88753-40-6 Benzoic acid (S)-4-benzyloxy-3-methanesulfonyloxy-butyl ester 
• 78513-07-2 ((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)methanol 
• 85418-26-4 Acetic acid (R)-3-acetoxy-1-benzyloxymethyl-propyl ester 
• 196861-65-1 (2R,4R)-4-Benzyloxymethyl-2-(4-methoxy-phenyl)-[1,3]dioxane 
• 760189-02-4 (R)-4-Benzyloxy-3-hydroxy-1-[(R)-4-(1-methyl-1-triethylsilanyloxy-ethyl)-2-thioxo-thiazolidin-3-yl]-butan-1-one 
• 745831-92-9 (R)-4-Benzyloxy-3-hydroxy-butyric acid (1R,2S)-1-(toluene-4-sulfonylamino)-indan-2-yl ester 
• 80885-30-9 (E)-4-(benzyloxy)-2-buten-1-ol 
• 69152-88-1 4-(benzyloxy)-2-buten-1-ol 
• 70005-88-8 (R)-1,2,4-butanetriol 
• 100-39-0 benzyl bromide 
• 88753-37-1 Benzoic acid (S)-4-benzyloxy-3-hydroxy-butyl ester 
• 85418-23-1 (S)-1-O-benzyl-1,2,4-butanetriol 

Downstream Products

• 115369-24-9 Toluene-4-sulfonic acid (R)-4-benzyloxy-3-hydroxy-butyl ester 
• 70005-88-8 (R)-1,2,4-butanetriol 
• 1321980-61-3 C₁₉H₂₄O₄ 
• 1321980-62-4 C₂₃H₂₈O₅ 
• 1321980-63-5 C₂₁H₂₆O₄ 
• 1321980-64-6 (3-{3-(benzyloxy)-2-[(4-methoxybenzyl)oxy]propyl}oxiran-2-yl)methanol 
• 1321980-67-9 2-azido-6-(benzyloxy)-5-(4-methoxybenzyloxy)hexane-1,3-diol 
• 1321980-71-5 C₁₆H₂₃N₃O₄ 
• 1321980-72-6 C₁₇H₂₅N₃O₆S 
• 1321980-73-7 (4aR,6S,7aS)-6-(benzyloxymethyl)-2,2-dimethylhexahydro[1,3]dioxino[5,4-b]pyrrole 
• 1321980-70-4 C₂₄H₃₁N₃O₅ 
• 264603-16-9 (3R)-4-benzyloxy-3-(4-methoxy-benzyloxy)-butyraldehyde 
• 115369-26-1 (R)-4-Benzenesulfonyl-1-benzyloxy-butan-2-ol 
• 115369-25-0 (R)-1-Benzyloxy-4-phenylsulfanyl-butan-2-ol 

Relevant articles and documents

Tin-mediated regioselective benzylation and allylation of polyols: Applicability of a catalytic approach under solvent-free conditions

The first catalytic version of the stannylene-mediated benzylation and allylation of polyols is reported. The methodology is based on a simple solvent-free protocol that significantly advances, in terms of both experimental ease and synthetic scope, the a

Organocatalysis in natural product synthesis: A simple one-pot approach to optically active β-diols

Optically active β-diols have been prepared using an organocatalytic one-pot approach from α,β-unsaturated aldehydes using (E)-benzaldehyde oxime as nucleophile in an oxa-Michael reaction with subsequent in situ reduction or Grignard addition. With this p

Stereoselective chloroacetate aldol reactions: Syntheses of acetate aldol equivalents and darzens glycidic esters

Aldol reaction of the Ti-enolate derived from cis-1-tosylamido-2-indanyl chloroacetate with representative aldehydes proceeded in excellent yield and high diastereoselectivities. Removal of chlorine provided alternative access to highly diastereoselective acetate aldol equivalents or the corresponding glycidic ester condensation products.