81131-39-7

Basic information

• Product Name: Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI)
• Synonyms: Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI);(1R,3S)-3-AMinocyclohexanecarboxylic Acid hydrochloride;(1R,3S)-3-Aminocyclohexanecarboxylic Acid;Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)-;(1R,3S)-3-AMINOCYCLOHEXANECARBOXYLIC ACID(WX191418)
• CAS NO: 81131-39-7
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18362
• Product Categories: AMINOACID
• Mol File: 81131-39-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: 279°C(lit.)
• Boiling Point: 280.0±33.0 °C(Predicted)
• Appearance: /
• Density: 1.133±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.99±0.10(Predicted)
• CAS DataBase Reference: Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI)(81131-39-7)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI)(81131-39-7)

Safety Data

• Hazardous Substances Data: 81131-39-7(Hazardous Substances Data)

Usage

General Description

Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI) is a chemical compound with a molecular formula C8H15NO2. It is a stereoisomer of cyclohexanecarboxylic acid with an amino group attached to the third carbon atom, in a configuration that represents the 1R,3S enantiomer. Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)- (9CI) is used in various chemical and pharmaceutical applications, including as a building block for the synthesis of other organic compounds. It may also be studied for its potential medicinal properties and biological activity, particularly in the context of drug development and research.

Upstream product

• 123-51-3 i-Amyl alcohol 
• 99-05-8 meta-aminobenzoic acid 
• 16205-98-4 3-oxo-cyclohexanecarboxylic acid 
• 4720-83-6 6-oxabicyclo[3.2.1]oct-3-en-7-one 
• 116724-13-1 trans rac-cyclohexyl 1,3-dicarboxylic acid 
• 81201-62-9 (d,l)-cis-3-phthalimidocyclohex-4-ene-1-carboxylic acid 
• 81202-29-1 (1R,5R)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclohex-3-enecarboxylic acid 
• 81086-73-9 ethyl cis-5-phthalimidocyclohex-3-ene-1-carboxylate 
• 586-38-9 3-Methoxybenzoic acid 
• 81086-72-8 5-Bromo-cyclohex-3-enecarboxylic acid ethyl ester 
• 21531-43-1 (R)-3-oxocyclohexanecarboxylic acid 
• 15111-56-5 ethyl-3-cyclohexene-1-carboxylate 
• 218772-92-0 (±)-cis-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid 
• 16636-51-4 (+/-)-cis-3-aminocyclohexanecarboxylic acid 

Downstream Products

• 53084-60-9 ethyl 3-aminocyclohexanecarboxylate 
• 511547-46-9 (1R,3S)-3-[(tert-butyloxycarbonyl)methylamino]cyclohexanecarboxylic acid 
• 869081-67-4 (1R,3S)-(9H-fluoren-9-yl)-methyl N-butoxycarbonyl-N-methyl-3-aminocyclohexanecarboxylate 
• 873552-45-5 Boc-[L-γ-Ach-D-^MeN-Ala]-OFm 
• 873552-48-8 Boc-[(L-γ-Ach-D-^MeN-Ala)2]-OFm 
• 873552-50-2 Boc-[(L-γ-Ach-D-^MeN-Ala)4]-OFm 
• 81131-39-7 (+/-)-cis-3-Aminocyclohexanecarboxylic acid 
• 1580507-71-6 3-(dimethylamino)cyclohexanecarboxylic acid hydrochloride 
• 36365-99-8 methyl 3-(dimethylamino)cyclohexanecarboxylate 
• 1580507-74-9 3-(methoxycarbonyl)-N,N,N-trimethylcyclohexanaminium iodide 
• 1580507-76-1 3-(trimethylammonio)cyclohexanecarboxylate 
• 1035324-95-8 3-(3,5-dimethoxybenzamido)cyclohexanecarboxylic acid 
• 244156-66-9 3-[3-(4-trifluoromethyl-phenyl)-ureido]-benzoic acid 
• 1070166-06-1 4-(3-carboxycyclohexylamino)-2-chloro-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid

An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid from 3-aminobenzoic acid is described utilising milder and more selective conditions. Both a classical salt resolution and an enzymatic approach have been shown to give the desired compound in high selectivity.

New cyclic peptide assemblies with hydrophobic cavities: The structural and thermodynamic basis of a new class of peptide nanotubes

A new class of self-assembling peptides based on cyclic peptides made of alternating 3-aminocyclohexanecarboxylic acid (γ-Acc) and α-amino acids is described. The studied cylindrical assemblies are models for a new class of self-assembling peptide nanotub

2-aminopyridine derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.