81449-01-6

Basic information

• Product Name: Methanone, [4-(hydroxyMethyl)phenyl]phenyl-
• Synonyms: Methanone, [4-(hydroxyMethyl)phenyl]phenyl-;(4-(HydroxyMethyl)phenyl)(phenyl)Methanone
• CAS NO: 81449-01-6
• Molecular Formula: C₁₄H₁₂O₂
• Molecular Weight: 212.24388
• Mol File: 81449-01-6.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methanone, [4-(hydroxyMethyl)phenyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [4-(hydroxyMethyl)phenyl]phenyl-(81449-01-6)
• EPA Substance Registry System: Methanone, [4-(hydroxyMethyl)phenyl]phenyl-(81449-01-6)

Safety Data

• Hazardous Substances Data: 81449-01-6(Hazardous Substances Data)

Usage

General Description

Methanone, [4-(hydroxymethyl)phenyl]phenyl- is a chemical compound with the molecular formula C15H14O2. It is also known by its IUPAC name 4'-Methoxyacetophenone or 4'-Hydroxyacetophenone. Methanone, [4-(hydroxymethyl)phenyl]phenyl- is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various pharmaceuticals and fine chemicals. It has a variety of applications, including as a fragrance ingredient in the cosmetics and personal care industries, as well as in the production of dyes and pigments. Additionally, it is also used as an intermediate in the production of certain agricultural chemicals and as a flavoring agent in the food industry.

Upstream product

• 15165-27-2 ethyl 4-benzoylbenzoate 
• 52010-97-6 4-(hydroxylmethyl)benzaldehyde 
• 623-27-8 terephthalaldehyde, 
• 88682-29-5 4-(1-hydroxy-1-phenylmethyl)benzyl alcohol 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 50-00-0 formaldehyd 
• 611-95-0 4-carboxybenzophenone 
• 1616844-72-4 methyl 4-(2-phenyl-1,3-dioxolan-2-yl)benzoate 
• 6158-54-9 methyl 4-Benzoylbenzoate 
• 134-85-0 4-chlorobenzophenone 
• 134-84-9 4-Methylbenzophenone 
• 67-56-1 methanol 
• 119-61-9 benzophenone 

Downstream Products

• 1146295-87-5 4-[(tributylstannyl)oxymethyl]-benzophenone 
• 20912-50-9 4-benzoylbenzaldehyde 
• 1008513-70-9 4-Hydroxymethyl benzophenone hydrazone 
• 201275-75-4 4-(allyloxymethyl)benzophenone 
• 74839-99-9 p-benzoylcinnamic acid 
• 205443-12-5 (3-Ethylsulfanyl-2,5-dioxo-pyrrolidin-1-yl)-acetic acid 4-(1-hydroxy-1-phenyl-2-propionylamino-ethyl)-benzyl ester 
• 205443-10-3 (3-Ethylsulfanyl-2,5-dioxo-pyrrolidin-1-yl)-acetic acid 4-benzoyl-benzyl ester 
• 205443-08-9 (2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-acetic acid 4-benzoyl-benzyl ester 
• 185686-39-9 (E,E)-[4-(2',6'-dimethyl-8'-tetrahydropyranyl-2''-oxy-octa-2',6'-dienyloxy)-methylphenyl]-phenyl-methanone 
• 30568-21-9 2.3.3-trichlor-1--propen-(2) 
• 30568-19-5 α-Chlor-p-benzoyl-hydrozimtsaeure-methylester 
• 30568-20-8 p-Benzoyl-zimtsaeure-methylester 

Relevant articles and documents

Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels

To locate the binding sites of general anesthetics on ligand-gated ion channels, two derivatives of the intravenous general anesthetic etomidate (2-ethyl 1-(phenylethyl)-1H-imidazole-5-carboxylate), in which the 2-ethyl group has been replaced by photoact

Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

Transition-metal-free, ambient-pressure carbonylative cross-coupling reactions of aryl halides with potassium aryltrifluoroborates

We disclose an unprecedented transition-metal-free carbonylative cross coupling of aryl halides with potassium aryl trifluoroborates even at atmospheric pressure of carbon monoxide. This protocol is efficient, operationally simple, and shows wide scope with regard to both aryl halides and potassium aryl trifluoroborates containing a series of active functional groups.