816462-34-7Relevant articles and documents
A Gold(I)-Catalyzed Hydroamination/Cycloisomerization Cascade: Concise Synthesis of (±)-seco-Antofine and (±)-Septicine
Tian, Guilong,Song, Liangliang,Li, Zhenghua,Robeyns, Koen,Van Meervelt, Luc,Van Der Eycken, Erik V.
supporting information, p. 8441 - 8445 (2020/11/03)
A concise and flexible procedure for the synthesis of highly functionalized N-heterocyclic 1,6-annulated 2-pyridones and 2,3-annulated 4-pyrimidinones has been elaborated through a gold-catalyzed tandem hydroamination/cycloisomerization cascade. This novel and highly efficient method allows the rapid construction of these diverse N-heterocyclic scaffolds starting from readily available building blocks, and shows a wide scope and good functional group tolerance. The total synthesis of (±)-seco-antofine and (±)-septicine were realized employing this strategy.
An efficient synthesis of neoflavonoid antioxidants based on Montmorillonite K-10 catalysis
Lee,Tseng,Lee
, p. 2247 - 2254 (2007/10/03)
A new approach to synthesis of neoflavonoids, based on a high yielding Montmorillonite K-10 catalyzed lactone ring forming cyclization process, is described. The utility of this methodology is exemplified by its employment in the preparation of the substituted 4-phenylneoflavonoids 1-8. The free radical scavenging properties of these substances were evaluated. The neoflavonoids 1 and 5, which mimic esculetin-type antioxidants, were observed to quench hydrazyl free radicals.
Synthesis of Amido-ureas and the Nature of Caracasanamide, the Hypotensive Principle of Verbesina caracasana
Crombie, Leslie,Jarrett, Sandra R. M.
, p. 3179 - 3184 (2007/10/02)
Syntheses of the (E)-1 and (Z)-2 forms of 1-(3-methylbut-2-enyl)-3-(4-butyl)urea, proposed structures for the natural hypotensive caracasanamide, have been carried out.The compounds were found not to be identical wit