81677-60-3 Usage
Description
(S)-4-Nitrophenylalaninemethylester, a derivative of the essential amino acid phenylalanine, is a chemical compound with a nitro group attached to its benzene ring. This attachment is responsible for its distinct yellow color. It is widely utilized in laboratory research for the synthesis of pharmaceutical and bioactive compounds. Due to its potential harmful effects if ingested or comes into contact with the skin or eyes, it is crucial to handle (S)-4-Nitrophenylalaninemethylester with caution.
Uses
Used in Pharmaceutical Synthesis:
(S)-4-Nitrophenylalaninemethylester is used as a precursor in the pharmaceutical industry for the synthesis of various pharmaceutical and bioactive compounds. Its unique chemical structure allows for the creation of a range of therapeutic agents.
Used in Laboratory Research:
In the field of laboratory research, (S)-4-Nitrophenylalaninemethylester is used as a key compound for studying the properties and interactions of amino acid derivatives. Its characteristic yellow color and reactivity make it a valuable tool for various experimental procedures.
Used in Chemical Education:
(S)-4-Nitrophenylalaninemethylester can also be employed in educational settings, particularly in chemistry courses, to demonstrate the synthesis and properties of amino acid derivatives. Its distinct color and reactivity make it an engaging and informative compound for students to study.
Check Digit Verification of cas no
The CAS Registry Mumber 81677-60-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,6,7 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81677-60:
(7*8)+(6*1)+(5*6)+(4*7)+(3*7)+(2*6)+(1*0)=153
153 % 10 = 3
So 81677-60-3 is a valid CAS Registry Number.
81677-60-3Relevant articles and documents
A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS
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Paragraph 000398; 000399, (2021/03/02)
The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.
Pd(II)-catalyzed C(sp3)-H arylation of amino acid derivatives with click-triazoles as removable directing groups
Zhang, Guofu,Xie, Xiaoqiang,Zhu, Jianfei,Li, Shasha,Ding, Chengrong,Ding, Ping
supporting information, p. 5444 - 5449 (2015/05/20)
By using click-triazoles as conveniently approachable and removable directing groups, the direct palladium-catalyzed C(sp3)-H arylation of amino acid derivatives with various aryl iodides bearing different electronic properties has been achieved. Notably, the desired amino acid molecule can be obtained by the cleavage of the tethered click-triazoles after the catalytic reaction, which aims to provide a practical protocol for the accessibility of both natural and synthetic amino acids.
Developing new chemical tools for DNA methyltransferase 1 (DNMT 1): A small-molecule activity-based probe and novel tetrazole-containing inhibitors
Zhu, Biwei,Ge, Jingyan,Yao, Shao Q.
, p. 2917 - 2927 (2015/03/30)
DNA methylation is an important epigenetic modification catalyzed by DNA methyltransferases (DNMTs). Abnormal expression of endogenous DNMTs in human causes alterations in the genome methylation patterns which subsequently lead to the development of cance
