81697-89-4

Basic information

• Product Name: 5-(5,5-Dimethyl-[1,3]dioxan-2-yl)-1H-pyrrole-2-carboxylic acid methyl ester
• CAS NO: 81697-89-4
• Molecular Weight: 239.271
• Mol File: 81697-89-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(5,5-Dimethyl-[1,3]dioxan-2-yl)-1H-pyrrole-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(5,5-Dimethyl-[1,3]dioxan-2-yl)-1H-pyrrole-2-carboxylic acid methyl ester(81697-89-4)
• EPA Substance Registry System: 5-(5,5-Dimethyl-[1,3]dioxan-2-yl)-1H-pyrrole-2-carboxylic acid methyl ester(81697-89-4)

Safety Data

• Hazardous Substances Data: 81697-89-4(Hazardous Substances Data)

Upstream product

• 1197-13-3 methyl 5-formyl-1H-pyrrole-2-carboxylate 

Relevant articles and documents

PYRROLE CHEMISTRY. XXIV. THE VILSMEIER FORMYLATION AND CYANATION OF PYRROLE ACETALS. A SYNTHESIS OF PYRROLE-2,3,5-TRICARBOXALDEHYDE

The preparation of the acetals of a number of pyrrole mono- and dicarboxaldehydes is described.It is shown that, provided the reactivity of the unsubstituted ring positions on the pyrrole nucleus is not too low, a carboxaldehyde or a carbonitrile group may be substituted on the pyrrole ring using the Vilsmeier reaction or chlorosulfonyl isocyanate respectively. Vilsmeier formylation of the diacetal, 2,4-di(5,5-dimethyl-1,3-dioxan-2-yl)-pyrrole, followed by hydrolysis gave pyrrole-2,3,5-tricarboxaldehyde.