82085-89-0

Basic information

• Product Name: 2-(4'-nitrophenyl)-1,2-dihydro-4H-3,1-benzoxazine
• Synonyms: 2-(4'-nitrophenyl)-1,2-dihydro-4H-3,1-benzoxazine
• CAS NO: 82085-89-0
• Molecular Weight: 256.261
• Mol File: 82085-89-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(4'-nitrophenyl)-1,2-dihydro-4H-3,1-benzoxazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4'-nitrophenyl)-1,2-dihydro-4H-3,1-benzoxazine(82085-89-0)
• EPA Substance Registry System: 2-(4'-nitrophenyl)-1,2-dihydro-4H-3,1-benzoxazine(82085-89-0)

Safety Data

• Hazardous Substances Data: 82085-89-0(Hazardous Substances Data)

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 16063-05-1 2-(4-nitrophenyl)-4H-3,1-benzoxazin-4-one 
• 196085-87-7 2-(4-nitro-phenyl)-4H-benzo[d][1,3]oxazine 

Relevant articles and documents

Simple grinding-induced reactions of 2-aminobenzyl alcohol and benzaldehyde derivatives, a rapid synthetic route to 3,1-benzoxazines

The grinding-induced reactions of 2-aminobenzyl alcohol and benzaldehyde derivatives in the presence of 30 mol% of acetic acid to give 3,1-benzoxazines are described. The reactions were performed at room temperature affording 3,1-benzoxazines in yields above 95% and high purity when benzaldehyde and its chloro and nitro derivatives were used.

Synthesis of 3h-quinazolin-4-ones and 4h-3,1-benzoxazin-4-ones via benzylic oxidation and oxidative dehydrogenation using potassium iodide-tert-butyl hydroperoxide

A simple and elegant method for benzylic activation was demonstrated employing the potassium iodide/tert-butyl hydrogen peroxide catalytic system. This methodology was further extended for the synthesis of biologically important heterocycles namely, 3H-quinazolin-4-ones and 4H-3,1-benzoxazin-4-ones including mecloqualone and etaqualone which are important quinazolinone-based drugs used for the treatment of insomnia in good yields.

Studies on the Benzoxazine Series. 2- Preparation and 1H and 13C NMR Structural Study of Some Substituted 1,2-Dihydro-4H-3,1-benzoxazines

In addition to the parent compounds, nine methyl-substituted 1,2-dihydro-4H-3,1-benzoxazines with and without N-methyl substitution were prepared.The chain tautomer could only be detected in the case of 1,2-dihydro-2-(p-nitrophenyl)-4H-3,1-benzoxazine in