82924-03-6 Usage
Uses
Enzyme inhibitor
(angiotensin-converting).
Enzyme inhibitor
This indole derivative (FWpentopril = 318.37 g/mol; CAS 82924-03-6), also known as CGS 13945, is an angiotensin I-converting enzyme inhibitor. The pharmacologically active metabolite is the diacid, known as pentoprilat and CGS 13934. Target(s): peptidyl-dipeptidase A, or angiotensin Iconverting enzyme; and Xaa-Trp aminopeptidase, or aminopeptidase W.
Check Digit Verification of cas no
The CAS Registry Mumber 82924-03-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,9,2 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 82924-03:
(7*8)+(6*2)+(5*9)+(4*2)+(3*4)+(2*0)+(1*3)=136
136 % 10 = 6
So 82924-03-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H23NO5/c1-4-24-18(23)12(3)9-11(2)16(20)19-14-8-6-5-7-13(14)10-15(19)17(21)22/h5-8,11-12,15H,4,9-10H2,1-3H3,(H,21,22)/t11-,12-,15+/m1/s1
82924-03-6Relevant articles and documents
1-Carboxyalkanoylindoline-2-carboxylic acids
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, (2008/06/13)
1-Carboxy-(alkanoyl or aralkanoyl)-indoline-2-carboxylic acids, e.g., those of the formula STR1 R=H, alkyl, alkoxy, halogeno or CF3 ; R'=H or R-phenyl; m=0 or 1; p,q=0 to 2; and derivatives thereof, are antihypertensive and cardioactive agents.
1-CARBOXYALKANOYLINDOLINE-2-CARBOXYLIC ACIDS
-
, (2008/06/13)
1-Carboxy-(alkanoyl or aralkanoyl)-indoline-2-carboxylic acids, e.g., those of the formula STR1 R=H, alkyl, alkoxy, halogeno or CF. sub.3 ; R'=H or R-phenyl;m=0 or 1;p, q=0 to 2; and functional derivatives thereof, are antihypertensive a