83160-78-5

Basic information

• Product Name: 5-aminomethyl-1,2,4-triazol-3-one
• Synonyms: 5-aminomethyl-1,2,4-triazol-3-one;5-(aminomethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one(SALTDATA: 2HCl);3-(AMinoMethyl)-1H-1,2,4-triazol-5(4H)-one;5-Aminomethyl-2,4-dihydro-[1,2,4]triazol-3-one;5-Oxo-4,5-dihydro-1H-[1,2,4]triazol-3-ylmethylamine;3-(aminomethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
• CAS NO: 83160-78-5
• Molecular Formula: C3H6N4O
• Molecular Weight: 114.11
• Mol File: 83160-78-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.89g/cm³
• Refractive Index: 1.801
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-aminomethyl-1,2,4-triazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-aminomethyl-1,2,4-triazol-3-one(83160-78-5)
• EPA Substance Registry System: 5-aminomethyl-1,2,4-triazol-3-one(83160-78-5)

Safety Data

• Hazardous Substances Data: 83160-78-5(Hazardous Substances Data)

Usage

General Description

5-Aminomethyl-1,2,4-triazol-3-one, also known as AMT, is a chemical compound that belongs to the class of triazolone derivatives. It has a molecular formula C3H5N3O and a molecular weight of 99.09 g/mol. AMT is a white crystalline powder that is soluble in water and methanol. It is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. AMT is also employed as a building block for the preparation of various nitrogen-containing heterocyclic compounds. Additionally, it has been studied for its potential applications in the field of medicine and materials science. Overall, 5-Aminomethyl-1,2,4-triazol-3-one is a versatile compound with diverse industrial and scientific uses.

InChI:InChI=1/C3H6N4O/c4-1-2-5-3(8)7-6-2/h1,4H2,(H2,5,6,7,8)

Upstream product

• 252742-72-6 3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one 

Relevant articles and documents

SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4,R3 is C1-6-alkyl which is substituted by R5 and R6,R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl,R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond andwherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen,and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.