252742-72-6Relevant articles and documents
Arab league swiss tanzania and luck sha pitan chain fragment preparation method (by machine translation)
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Paragraph 0022, (2019/04/06)
The invention relates to a process for preparing arab league swiss tanzania and luck sha pitan chain fragment of the new method, in particular to the preparation of 5 - chloromethyl - 2, 4 - dihydro [1, 2, 4] triazole - 3 - ones. This method uses the 2 - benzyloxy bromide and animal pen amidogen chloride as the starting material, first of all the one-pot synthesis to achieve 5 - hydroxymethyl - 2, 4 - dihydro [1, 2, 4] triazole - 3 - ketone preparation, then 5 - hydroxymethyl - 2, 4 - dihydro [1, 2, 4] triazole - 3 - ketone SOCl2 Under the effect of the 5 - chloromethyl - 2, 4 - dihydro [1, 2, 4] triazole - 3 - one of the preparation. (by machine translation)
NOVEL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS
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Page/Page column 65, (2017/07/14)
Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme:(I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS
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Page/Page column 27, (2012/02/06)
The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4,R3 is C1-6-alkyl which is substituted by R5 and R6,R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl,R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond andwherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen,and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.