83266-41-5

Basic information

• Product Name: 3-[(3-chlorophenyl)amino]-1-phenyl-1-propanone
• Synonyms: 3-[(3-chlorophenyl)amino]-1-phenyl-1-propanone
• CAS NO: 83266-41-5
• Molecular Weight: 259.735
• Mol File: 83266-41-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-[(3-chlorophenyl)amino]-1-phenyl-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(3-chlorophenyl)amino]-1-phenyl-1-propanone(83266-41-5)
• EPA Substance Registry System: 3-[(3-chlorophenyl)amino]-1-phenyl-1-propanone(83266-41-5)

Safety Data

• Hazardous Substances Data: 83266-41-5(Hazardous Substances Data)

Upstream product

• 108-42-9 3-chloro-aniline 
• 768-03-6 Phenyl vinyl ketone 
• 71-43-2 benzene 
• 936-59-4 3-chloropropiophenone 
• 879-72-1 3-(dimethylamino)propiophenone hydrochloride 
• 5409-66-5 3-benzoyl-4-hydroxy-1-methyl-4-phenylpiperidine 

Downstream Products

• 1048974-51-1 1-phenyl-3-(3-chlorphenyl)-6-phenyl-3,4-dihydropyrimidin-2(1H)-one 
• 1048974-50-0 1-(4-chlorophenyl)-3-(3-chlorphenyl)-6-phenyl-3,4-dihydropyrimidin-2(1H)-one 
• 156950-85-5 3-(3-Chloro-phenylamino)-1-phenyl-propan-1-ol 

Relevant articles and documents

I2-Promoted Intramolecular Oxidative Cyclization of Butenyl Anilines: A Facile Route to Benzo[b]azepines

A metal-free approach for the synthesis of seven-membered N-heterocycles has been developed by the I2-promoted intramolecular cross-coupling/annulation of butenyl anilines. This cyclization reaction involves C?H activation and C?C bond formation and exhibits good functional group tolerance. A series of benzo[b]azepine derivatives are obtained in moderate to good yields.

A convenient synthesis of novel 1,3,4-triaryl-3,4-dihydropyrimidin-2(1H)- ones by cyclization of aromatic isocyanates with β-arylamino-1- phenylpropan-1-ones

(Chemical Equation Presented) A simple one-step method for preparation of novel 1,3,4-triaryl-3,4-dihydropyrimidin-2(1H)-ones has been developed by reaction of aromatic isocyanates with β-arylamino-1-phenylpropan-1-ones in refluxing toluene in the presence of KHSO4 and HCl.

Reaction of 3-benzoyl-1-methyl-4-phenyl-γ-piperidol with arylamines and arylhydrazines. Synthesis of 3-arylamino-1-oxo-1-phenylpropanes and 1,3 diarylpyrazoles and their fragmentation under electron impact

Upon heating in the presence of arylamines 3-benzoyl-4-hydroxy-1-methyl-4- phenylpiperidine decyclizes via a retroaldol type reaction with subsequent transamination of the intermediate Mannich base to give 3-arylamino-1-oxo-1- phenylpropanes. In the case of the use of arylhydrazines this γ-piperidol recyclizes to give 1,3-diarylpyrazoles and their 4,5-dihydro derivatives. The mass spectroscopic behavior of a series of 3-arylamino-substituted 1-phenylpropanones has been studied.