833485-11-3

Basic information

• Product Name: methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate
• Synonyms: methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate
• CAS NO: 833485-11-3
• Molecular Weight: 335.197
• Mol File: 833485-11-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate(833485-11-3)
• EPA Substance Registry System: methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate(833485-11-3)

Safety Data

• Hazardous Substances Data: 833485-11-3(Hazardous Substances Data)

Upstream product

• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 916243-38-4 methyl 2-{4-[(2-bromobenzyl)oxy]-3-(4-hydroxybut-1-yn-1-yl)phenyl}acetate 
• 916243-37-3 methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate 
• 1354633-53-6 C₂₀H₂₂O₄ 
• 1354633-50-3 C₂₀H₂₀O₄ 
• 916243-39-5 (Z)-methyl 2-[11-(3-hydroxypropylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl]acetate 
• 140462-76-6 olopatadine hydrochloride 
• 113806-05-6 olopatadine 

Relevant articles and documents

A new efficient synthetic route for the synthesis of the antiallergic drug, olopatadine hydrochloride, via stereospecific palladium-catalyzed reaction

A new practical and efficient synthetic route for the synthesis of olopatadine hydrochloride via the intramolecular stereospecific seven-membered ring cyclization from an alkyne intermediate using palladium catalyst and hydride source was established. Furthermore, the optimization of that key stereospecific reaction was examined by design of experiment (DoE), and the desired Z-isomer could be obtained with high yield.