916243-37-3

Basic information

• Product Name: methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate
• Synonyms: methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate
• CAS NO: 916243-37-3
• Molecular Weight: 461.094
• Mol File: 916243-37-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate(916243-37-3)
• EPA Substance Registry System: methyl 2-{4-[(2-bromobenzyl)oxy]-3-iodophenyl}acetate(916243-37-3)

Safety Data

• Hazardous Substances Data: 916243-37-3(Hazardous Substances Data)

Upstream product

• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 833485-11-3 methyl 2-{4-[(2-bromobenzyl)oxy]phenyl}acetate 

Downstream Products

• 1354633-53-6 C₂₀H₂₂O₄ 
• 1354633-50-3 C₂₀H₂₀O₄ 
• 916243-39-5 (Z)-methyl 2-[11-(3-hydroxypropylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl]acetate 
• 140462-76-6 olopatadine hydrochloride 
• 916243-38-4 methyl 2-{4-[(2-bromobenzyl)oxy]-3-(4-hydroxybut-1-yn-1-yl)phenyl}acetate 
• 113806-05-6 olopatadine 

Relevant articles and documents

Novel and Efficient Synthesis of Deuterium-Labeled Olopatadine-d6

A novel and highly efficient synthetic approach has been developed for the synthesis of deuterium-labeled olopatadine-d6 using inexpensive and commercially available dimethyl sulfate-d6 at the stage of alkylation of primary amine intermediate. The proposed synthetic path makes it possible to avoid the use of expensive labeled reagents such as dimethyl amine-d6 used as labeled precursor in the traditional synthetic route. The structure of the obtained olapatadine-d6 has been confirmed by 1H NMR and mass spectral data.