83398-53-2Relevant articles and documents
Conformation of [1-13C, 15N]acetyl-L-carnitine. Rotational-echo, double-resonance nuclear magnetic resonance spectroscopy
Anderson, Robert C.,Gullion, Terry,Joers, Jim M.,Shapiro, Michael,Villhauer, Edwin B.,Weber, Hans Peter
, p. 10546 - 10550 (1995)
The conformation of [1-13C, 15N]acetyl-L-carnitine is studied by rotational-echo, double-resonance (REDOR) NMR experiments. The REDOR results show that acetyl-L-carnitine adopts an extended molecular conformation in the solid state f
Preparation of optically active 1,2-diol monotosylates by enzymatic hydrolysis
Shimada, Yasutaka,Sato, Hiroshi,Minowa, Shinji,Matsumoto, Kazutsugu
, p. 367 - 370 (2008/04/01)
An easy preparation of optically active 1,2-diol monotosylate derivatives by enzymatic hydrolysis is disclosed. Lipase PS (Burkholderia cepacia) catalyzes the hydrolysis of racemic 2-acetoxyhexyl tosylate with excellent enantioselectivity to afford the corresponding optically active compounds. In this reaction, a unique temperature effect is observed. After optimizing the reaction conditions, this procedure is widely applicable to the practical preparation of both enantiomers of various optically active compounds with high ee. Georg Thieme Verlag Stuttgart.
Selective Additions of Gaseous Hydrochloric Acid to Crystalline Epoxides und Steroid-Epoxides
Kaupp, Gerd,Ulrich, Anke,Sauer, Gerhard
, p. 383 - 390 (2007/10/02)
Solid epoxides add gaseous HCl or KBr regioselectively and without melting, if the melting points are sufficiently high.Such additions proceed diastereoselectively with chiral epoxides.These gas/solid reactions are compared to similar transformations in solution.One observes interesting reaction sequences in the conversions of steroidal epoxides.Thus the opening of the epoxide ring may be followed by cationic rearrangements, or it occurs elimination od water, if it creates conjugation to a carbonyl group.