84174-25-4

Basic information

• Product Name: p-fluorobenzylamine formamide
• Synonyms: p-fluorobenzylamine formamide
• CAS NO: 84174-25-4
• Molecular Weight: 153.156
• Mol File: 84174-25-4.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: p-fluorobenzylamine formamide(CAS DataBase Reference)
• NIST Chemistry Reference: p-fluorobenzylamine formamide(84174-25-4)
• EPA Substance Registry System: p-fluorobenzylamine formamide(84174-25-4)

Safety Data

• Hazardous Substances Data: 84174-25-4(Hazardous Substances Data)

Upstream product

• 16712-16-6 ammonium formate 
• 459-57-4 4-fluorobenzaldehyde 
• 124-38-9 carbon dioxide 
• 140-75-0 para-fluorobenzylamine 
• 64-18-6 formic acid 
• 123-76-2 levulinic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 77287-34-4 formamide 
• 67-56-1 methanol 
• 1194-02-1 4-fluorobenzonitrile 
• 201230-82-2 carbon monoxide 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 405-66-3 (4-Fluoro-benzyl)-methyl-amine 
• 148890-53-3 4-fluorobenzyl isocyanide 
• 148858-16-6 3-(4-fluorophenyl)-4,5-dihydroimidazo[1,5-a]quinoxaline 
• 180207-99-2 7-Fluoro-3-(4-fluoro-phenyl)-4,5-dihydro-imidazo[1,5-a]quinoxaline 
• 180207-98-1 6-Chloro-3-(4-fluoro-phenyl)-4,5-dihydro-imidazo[1,5-a]quinoxaline 
• 180207-97-0 7-Chloro-3-(4-fluoro-phenyl)-4,5-dihydro-imidazo[1,5-a]quinoxaline 
• 180207-87-8 5-tert-Butyl-3-(4-fluoro-phenyl)-4,5-dihydro-imidazo[1,5-a]quinoxaline 
• 148858-14-4 5-tert-butyl-3-(4-fluorophenyl)-4,5-dihydroimidazo[1,5-a]quinoxalin-4-one 
• 1026714-68-0 3-(4-Fluoro-phenyl)-4H-imidazo[1,5-a]quinoxaline-5-carbonyl chloride 

Relevant articles and documents

Chromium-catalysed efficient: N -formylation of amines with a recyclable polyoxometalate-supported green catalyst

A simple and efficient protocol for the formylation of amines with formic acid, catalyzed by a polyoxometalate-based chromium catalyst, is described. Notably, this method shows excellent activity and chemoselectivity for the formylation of primary amines; diamines have also been successfully employed. Importantly, the chromium catalyst is potentially non-toxic, environmentally benign and safer than the widely used high valence chromium catalysts such as CrO3 and K2Cr2O7. The catalyst can be recycled several times with a negligible impact on activity. Finally, a plausible mechanism is provided based on the observation of intermediate and control experiments.

Bifunctional Ru-loaded Porous Organic Polymers with Pyridine Functionality: Recyclable Catalysts for N-Formylation of Amines with CO2 and H2

A series of pyridine functionalized porous organic polymers (POPs-Py&PPh3) have been synthesized by polymerizing tris(4-vinylphenyl)phosphane and 4-vinylpyridine. The pyridine moieties in the copolymer materials contribute to CO2 adsorption and promote the subsequent conversion of CO2. The POP supported Ru catalyst (Ru/POP3-Py&PPh3) shows a high catalytic activity (TON up to 710) in the N-formylation of various primary and secondary amines with CO2/H2, affording the corresponding formamides in good yields (55–95%) under mild reaction conditions. The heterogeneous catalyst can be easily separated from the reaction system and reused for at least eight cycles in the N-formylation of morpholine. (Figure presented.).

SUBSTITUTED PYRROLIDINE AMIDES IV

The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.