844639-06-1 Usage
Description
O-TriphenylMethoxy Quetiapine is an impurity of Quetiapine hemifumarate (Q510000), a dibenzothiazepine antipsychotic medication used in the treatment of schizophrenia.
Uses
Used in Pharmaceutical Industry:
O-TriphenylMethoxy Quetiapine is used as an impurity in the production of Quetiapine hemifumarate, a dibenzothiazepine antipsychotic medication. It is important to monitor and control the levels of this impurity to ensure the safety and efficacy of the medication in treating schizophrenia.
Check Digit Verification of cas no
The CAS Registry Mumber 844639-06-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,4,6,3 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 844639-06:
(8*8)+(7*4)+(6*4)+(5*6)+(4*3)+(3*9)+(2*0)+(1*6)=191
191 % 10 = 1
So 844639-06-1 is a valid CAS Registry Number.
844639-06-1Relevant articles and documents
PROCEDURE FOR PREPARING A PHARMACEUTICALLY ACTIVE COMPOUND
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Page/Page column 14; 15, (2008/06/13)
The invention relates to a procedure for preparing quetiapine by reaction between a compound of formula (II) and a compound of formula (III), in which X means a leaving group and P a protective group of alcohols resistant to alkaline conditions, in the presence of a base, followed by a step of deprotection and, optionally, obtaining a pharmaceutically acceptable salt thereof. Said procedure permits the obtaining of quetiapine with a high degree of purity under soft temperature conditions, with short reaction times and avoiding the use of toxic solvents.
