850211-97-1

Basic information

• Product Name: 3-Quinolinecarboxylic acid, 1-[3-[4-[[(2S)-2-[bis(ethylthio)methyl]-1-pyrrolidinyl]carbonyl]-2-methoxy- 5-nitrophenoxy]propyl]-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester
• CAS NO: 850211-97-1
• Molecular Formula: C32H37F2N3O8S2
• Molecular Weight: 693.79
• Mol File: 850211-97-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Quinolinecarboxylic acid, 1-[3-[4-[[(2S)-2-[bis(ethylthio)methyl]-1-pyrrolidinyl]carbonyl]-2-methoxy- 5-nitrophenoxy]propyl]-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 1-[3-[4-[[(2S)-2-[bis(ethylthio)methyl]-1-pyrrolidinyl]carbonyl]-2-methoxy- 5-nitrophenoxy]propyl]-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester(850211-97-1)
• EPA Substance Registry System: 3-Quinolinecarboxylic acid, 1-[3-[4-[[(2S)-2-[bis(ethylthio)methyl]-1-pyrrolidinyl]carbonyl]-2-methoxy- 5-nitrophenoxy]propyl]-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester(850211-97-1)

Safety Data

• Hazardous Substances Data: 850211-97-1(Hazardous Substances Data)

Upstream product

• 127810-77-9 (2S)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl dithioacetal 
• 3863-11-4 3,4-difluoroaniline 
• 111760-35-1 ethyl 6,7-difluoro-4-hydroxy-3-quinolinecarboxylate 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 142354-87-8 diethyl 2-[(3,4-difluorophenylamino)methylene]malonate 
• 850211-96-0 ethyl 1-(3-bromopropyl)-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate 
• 140647-02-5 (2S)-N-(4-hydroxy-5-methoxy-2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Relevant articles and documents

Synthesis and biological activity of fluoroquinolone-pyrrolo[2,1-c][1,4] benzodiazepine conjugates

Fluoroquinolones have been synthesized and linked to DC-81 at C8 position through different alkyl chain spacers. These PBD conjugates have exhibited good DNA binding affinity, and a representative compound shows promising in vitro anticancer activity.