850212-04-3Relevant articles and documents
Synthesis and biological activity of fluoroquinolone-pyrrolo[2,1-c][1,4] benzodiazepine conjugates
Kamal, Ahmed,Devaiah,Laxma Reddy,Shiva Kumar
, p. 2021 - 2029 (2007/10/03)
Fluoroquinolones have been synthesized and linked to DC-81 at C8 position through different alkyl chain spacers. These PBD conjugates have exhibited good DNA binding affinity, and a representative compound shows promising in vitro anticancer activity.