85031-60-3

Basic information

• Product Name: 4α-hydroperoxy-amorph-5-en-12-oic acid
• Synonyms: 4α-hydroperoxy-amorph-5-en-12-oic acid
• CAS NO: 85031-60-3
• Molecular Weight: 268.353
• Mol File: 85031-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4α-hydroperoxy-amorph-5-en-12-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4α-hydroperoxy-amorph-5-en-12-oic acid(85031-60-3)
• EPA Substance Registry System: 4α-hydroperoxy-amorph-5-en-12-oic acid(85031-60-3)

Safety Data

• Hazardous Substances Data: 85031-60-3(Hazardous Substances Data)

Upstream product

• 85031-59-0 dihydroartemisinic acid 

Downstream Products

• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 
• 104196-16-9 (3R,3a,6R,6aS,10aS)-3a,4,5,6,6a,7,8,8a-octahydro-3,6,9-trimethylnaphtho[8a,1-b]furan-2(3H)-one 
• 105231-07-0 (4R,4aS,7R,8S)-4,7-Dimethyl-8-(3-oxo-butyl)-4,4a,5,6,7,8-hexahydro-isochromen-3-one 
• 87206-33-5 (3R)-dihydroarteannuin B 
• 207446-83-1 arteanniun H 

Relevant articles and documents

The mechanism of the spontaneous autoxidation of dihydroartemisinic acid

Dihydroartemisinic acid undergoes slow spontaneous autoxidation to artemisinin and other natural products, which have been reported from the medicinal plant Artemisia annua. The mechanism of this complex transformation is shown to involve four steps: (i) initial reaction of the Δ4.5-double bond of dihydroartemisinic acid with molecular oxygen, (ii) Hock cleavage of the resulting tertiary allylic hydroperoxide; (iii) oxygenation of the enol product from Hock cleavage; and (iv) cyclization of the resulting vicinal hydroperoxyl-aldehyde to the 1,2,4-trioxane system of artemisinin.