85118-28-1 Usage
Description
Ethyl 3-(dimethylamino)butyrate is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals. It is characterized by its ester functional group and the presence of a dimethylamino group, which contributes to its reactivity and potential applications in the chemical and pharmaceutical industries.
Uses
Used in Pharmaceutical Industry:
Ethyl 3-(dimethylamino)butyrate is used as an intermediate in the synthesis of Dimethylthiambutene Hydrochloride (D479490), an opioid analgesic drug utilized in veterinary medicine. Its role in the production of this pain-relieving medication highlights its importance in the development of effective treatments for animals in need of pain management.
Check Digit Verification of cas no
The CAS Registry Mumber 85118-28-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,1,1 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85118-28:
(7*8)+(6*5)+(5*1)+(4*1)+(3*8)+(2*2)+(1*8)=131
131 % 10 = 1
So 85118-28-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H17NO2/c1-5-11-8(10)6-7(2)9(3)4/h7H,5-6H2,1-4H3
85118-28-1Relevant articles and documents
Alkoxide activation of aminoboranes towards selective amination
Sole, Cristina,Fernandez, Elena
supporting information, p. 11351 - 11355 (2013/11/06)
Piece of the (inter)action: The interaction of alkoxides with the sp 2 Bpin (pin=pinacol) moiety in aminoboranes forms the in situ Lewis acid-base adduct [RO-→B(OR)2-N(R′)2] which enables the amino moiety to react as a strong nucleophile with several electrophiles, thus providing amino alcohols, β-enamino esters, and β-hydroxy amides in a direct and remarkably selective way (see scheme). Copyright
New synthesis of β-aminoacid derivatives via hydroamination in Dimcarb
Hess,Dunkel,Muller
, p. 591 - 597 (2007/10/02)
A new selective hydro-dimethylamination method for unsaturated carboxylic acid derivatives with the pronucleophilic dimethylamine-precursor Dimcarb is described, which allows effective synthesis of hydro-β-dimethylamino-acid derivatives and unsaturated amides. Simple HMO quantum chemical calculation together with 1H NMR examination permits the prediction of suitable substrates, coupling position for dimethylamine as well as for mechanistical insights and optimal reaction course.