852288-18-7Relevant articles and documents
Medical intermediate compound and synthesis method thereof
-
Paragraph 0066; 0068-0069; 0071-0072; 0074, (2019/08/02)
The invention provides a medical intermediate compound and a synthesis method thereof and belongs to the field of medicine synthesis. The compound has the structural formula shown in the description,wherein the substance shown in the description is obtain
Method of Synthesizing Acetonide-Protected Catechol-Containing Compounds and Intermediates Produced Therein
-
, (2010/04/30)
The inventors disclose here a novel, facile approach to the synthesis of acetonide-protected catechol-containing compounds having at least one amine group. In specific embodiments, the invention provides novel methods of synthesizing 3,4-dihydroxyphenylalanine (H-DOPA(acetonide)-OH (6)), Fmoc-protected H-DOPA(acetonide)-OH (Fmoc-DOPA(acetonide)-OH (7)), Fmoc-protected dopamine (Fmoc-dopamine(acetonide) (10)), TFA-protected dopamine (TFA-dopamine(acetonide) (13)) and acetonide-protected 4-(2-aminoethyl)benzene-1,2-diol (acetonide-protected dopamine (14)).