852395-26-7

Basic information

• Product Name: methyl (1S,4'S,5R,5'S,6S)-6-fluoro-4-oxo-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate
• Synonyms: methyl (1S,4'S,5R,5'S,6S)-6-fluoro-4-oxo-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate
• CAS NO: 852395-26-7
• Molecular Weight: 382.388
• Mol File: 852395-26-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (1S,4'S,5R,5'S,6S)-6-fluoro-4-oxo-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1S,4'S,5R,5'S,6S)-6-fluoro-4-oxo-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate(852395-26-7)
• EPA Substance Registry System: methyl (1S,4'S,5R,5'S,6S)-6-fluoro-4-oxo-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate(852395-26-7)

Safety Data

• Hazardous Substances Data: 852395-26-7(Hazardous Substances Data)

Upstream product

• 852395-27-8 (4S,5S)-2,2,7,7-tetramethyl-4,5-diphenyl-3,6-dioxa-2,7-disilaoctane 
• 49825-99-2 (-)-trans-2-methoxycarbonylmethylcyclopent-3-en-1-ol 
• 852395-20-1 methyl (1R,2R,4S,5S,6R)-2-{[tert-butyl(dimethyl)silyl]oxy}-6-fluoro-4-hydroxybicyclo[3.1.0]hexane-6-carboxylate 
• 852395-21-2 methyl (1R,2R,5S,6S)-2-{[tert-butyl(dimethyl)silyl]oxy}-6-fluoro-4-oxobicyclo[3.1.0]hexane-6-carboxylate 
• 866920-87-8 methyl (2S)-((1R,2R,3R,5S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-oxabicyclo[3.1.0]hex-2-yl)(fluoro) acetate 
• 852395-22-3 methyl (1R,2R,5S,6S)-6-fluoro-2-hydroxy-4-oxobicyclo[3.1.0]hexane-6-carboxylate 
• 866920-86-7 methyl (2S)-fluoro[(1R,2S,3R,5S)-3-hydroxy-6-oxabicyclo[3.1.0]hex-2-yl] acetate 
• 866920-85-6 methyl (2S)-fluoro[(1R,5R)-5-hydroxycyclopent-2-en-1-yl] acetate 
• 852395-25-6 methyl (1S,4R,4'S,5R,5'S,6S)-6-fluoro-4-hydroxy-4',5'-diphenylspiro[bicyclo[3.1.0]hexane-2,2'-[1,3]dioxolane]-6-carboxylate 

Relevant articles and documents

Stereoselective syntheses of highly functionalized bicyclo[3.1.0]hexanes: A general methodology for the synthesis of potent and selective mGluR2/3 agonists

A Et3Al mediated intramolecular epoxide opening, cyclopropanation reaction is described. The transformation provided highly functionalized bicyclo[3.1.0]hexane systems in high efficiency and with perfect H or F endo selectivity. Application of