855288-74-3

Basic information

• Product Name: phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone
• Synonyms: phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone
• CAS NO: 855288-74-3
• Molecular Weight: 334.417
• Mol File: 855288-74-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone(855288-74-3)
• EPA Substance Registry System: phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone(855288-74-3)

Safety Data

• Hazardous Substances Data: 855288-74-3(Hazardous Substances Data)

Upstream product

• 610-71-9 2,5-dibromobenzoic acid 
• 17572-77-9 (3E)-1,4-diphenylbut-3-en-1-one 
• 122-78-1 phenylacetaldehyde 
• 104429-44-9 (Z)-5-(4-methylphenyl)-3-phenylpent-2-en-4-ynal 
• 56-23-5 tetrachloromethane 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 768-03-6 Phenyl vinyl ketone 
• 936-59-4 3-chloropropiophenone 
• 127-09-3 sodium acetate 
• 3420-52-8 1,4-Diphenylprop-3-en-1-one 
• 98-86-2 acetophenone 

Downstream Products

• 92-94-4 [1,1';4',1'']terphenyl 

Relevant articles and documents

Synthesis of Acyl Terphenyls and Higher Polyaromatics via Base-Promoted C-H Functionalization of Acetylarenes with Arylacetylenes

KOtBu/DMSO-promoted C-H functionalization of acetylarenes with arylacetylenes (100°C, 30 min), generating β,γ-ethylenic ketones, triggers upon further heating (100°C, 4 h, with or without acidifying additive) the cascade assembly of acyl terphenyls and higher polyaromatics in good yields.

Base-catalyzed cascade dimerization of γ-aryl-β,γ-enones into acylated terphenyls

4-Aryl-1-(het)arylbut-3-en-1-ones dimerize smoothly in the ButOK/DMSO superbase system at 100?°C for 4 h to afford acylated terphenyls in up to 79% yield. The dimerization is accompanied by elimination of the methylarene molecule.

Lewis acid-catalyzed [4 + 2] benzannulation between enynal units and enols or enol ethers: Novel synthetic tools for polysubstituted aromatic compounds including indole and benzofuran derivatives

The reaction of enynals 1, including o-(alkynyl)benzaldehydes, and carbonyl compounds 2, such as aldehydes and ketones, in the presence of a catalytic amount of AuBr3 in 1,4-dioxane at 100 °C gave the functionalized aromatic compounds 3 in high yields. Similarly, the AuBr3-catalyzed reactions of 1 with acetal compounds 5 afforded the corresponding aromatic compounds 3 in good yields. On the other hand, when the reaction was carried out in the presence of a catalytic amount of Cu(NTf2)2 and 1 equiv of H2O in (CH2Cl)2 at 100 °C, the decarbonylated naphthalene products 4 were obtained selectively over 3. Benzofused heteroaromatic compounds, such as indole derivatives 13 and benzofuran derivatives 15, were also synthesized by using the present benzannulation methodology.